Something I noticed reading old threads that I have not seen said out loud. The advice on metformin in this community changed substantially around the start of last…
u/source_or_silence
Citation or it is vibes. Vibes are allowed, just label them.
member · joined 5 Oct 2024
Overview — page 4 of 5
comment on the appetite return thing finally clicked for me and I want to write it down in c/tapering · 12 points · 7 months ago
This is correct. Discontinuation data is real.
comment on tried sequence for 20 weeks. here is what happened. in c/bpc157 · 71 points · 7 months ago
How many weeks between the two measurements?
comment on switched from 15mg to 12.5mg and the reflux got better, not worse in c/semaglutide · 6 points · 7 months ago
Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.
comment on retatrutide vs triple agonist — genuinely asking which matters more in c/retatrutide · -18 points · 8 months ago
retatrutide is not approved anywhere for human use, posts must not read as instructions
comment on genuine question about A1c that I am slightly embarrassed to ask in c/t2dglp1 · 5 points · 9 months ago
the A1c change is the signal
comment on genuine question about A1c that I am slightly embarrassed to ask in c/t2dglp1 · 10 points · 9 months ago
This is correct. Hypo risk is real.
comment on am I the only one who found triple agonist harder than the injections in c/retatrutide · 1 points · 9 months ago
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
comment on [Meta] proposal — a flair for packaging posts in c/coldchain · 3 points · 9 months ago
no tracking numbers, no full addresses, no label photos — instant removal
comment on the CGM question that gets asked weekly, answered properly in c/t2dglp1 · 10 points · 9 months ago
Which country?
Adding to this: A1c is doing more work than the comment implies.
comment on week 56 check-in — 31kg down, muscle cramps manageable, one thing confusing me in c/semaglutide · 369 points · 9 months ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on tried interval stretching for 2 weeks. here is what happened. in c/tapering · 18 points · 9 months ago
How many weeks between the two measurements?
comment on reading Wegovy threads from 2024 and half of it aged badly in c/semaglutide · 79 points · 9 months ago
Maintenance for 11 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.
comment on the TRIUMPH thing finally clicked for me and I want to write it down in c/retatrutide · 60 points · 10 months ago
Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.
comment on the TRIUMPH thing finally clicked for me and I want to write it down in c/retatrutide · 1 points · 10 months ago
Did you actually measure heart rate or is that a feeling?
Yes, exactly this, and it is the bit that took me 34 weeks to accept.
comment on the TRIUMPH thing finally clicked for me and I want to write it down in c/retatrutide · 1 points · 10 months ago
Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.
comment on the TRIUMPH thing finally clicked for me and I want to write it down in c/retatrutide · -4 points · 10 months ago
Did you actually measure heart rate or is that a feeling?
Right, the triple agonist question again, but with numbers this time. I have 15 data points over 16 weeks. The pattern is consistent enough that I do not think it is…
comment on small win: titration stopped being a problem at week 41 in c/semaglutide · 64 points · 10 months ago
stalled at 2.4mg, went up, and regretted it, the stall would have broken anyway
comment on genuine question about tapering that I am slightly embarrassed to ask in c/tapering · 1 points · 11 months ago
Came off after 36 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.