u/yara_boateng

Did they post the raw trace or just the summary?

Crossposting this to c/bpc157 because the people who need it are not reading this community.

Yeah, the chromatogram profile matters more than the headline number.

related substances are where the story lives, not the main peak

A shoulder on the main peak that 17 analysts integrated 11 different ways.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.

This is correct. ATTAIN data is phase 8.

Strongly agree. The supply impact would be huge.

This is correct. ApoB is the better marker.

Small correction: the trial was 16 weeks, not 39. Does not change your point but people will quote it.

stalled at 2.4mg, went up, and regretted it, the stall would have broken anyway

Slight fix: the number was 96.8, not 98.6. Decimal point, but a fairly consequential one.

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

okay but what dose of sema are you on

This is the correct method framing. Column and gradient are load-bearing fields.

ApoB from 19 to 4 is movement, not noise

Strongly agree. ALT is where you catch the liver story early.

This is the "correlation is mechanism" thing again. You changed three variables at once.

Crossposting this to c/researchpeptides because the people who need it are not reading this community.