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c/bloodwork·posted 1 year ago by u/pavel_nkemelu

help me understand ferritin, I have read the wiki twice

Discussion Slow Clap ×9 Well Actually ×2 Clean Column ×1

Trying to settle this properly because the thread from last year went in circles.

The claim: eGFR matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 4 months without either producing anything.

What would actually settle it is 7 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.

If you have data, post the data. If you have an opinion, flair it as an opinion.

3,987 up / 519 down88% upvoted49 commentsid 11klpo15 Aug 2024

49 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/step_therapy_s658 points·1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/micro_bump_mick398 points·1 year ago

eGFR noise during rapid loss is expected

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u/nnt_nate577 points·1 year ago

This is correct. ApoB is the better marker.

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u/emil_agyeman372 points·1 year ago

redact identifying details from lab PDFs before posting

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u/thyroid_tangent206 points·1 year ago

Yeah, baseline matters more than any later number.

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u/cormac_erdogan340 points·1 year ago

Strongly agree. ALT is where you catch the liver story early.

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u/intent_to_treat103 points·1 year ago

Slight fix: the number was 98.9, not 99.0. Decimal point, but a fairly consequential one.

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u/pavel_nkemelu-14 points·1 year ago

This is correct. ApoB is the better marker.

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u/karl_fischer_kev-21 points·1 year ago

ALT is where the fatty-liver story shows up first

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u/elin_trevino1 point·1 year ago

ALT is where the fatty-liver story shows up first

Yes, exactly this, and it is the bit that took me 39 weeks to accept.

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u/pavel_nkemeluOP1 point·1 year ago

Not to be pedantic but ALT and A1c are being used interchangeably and they are not interchangeable in real life.

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u/noor_cardoso0 points·1 year ago

HOMA-IR is crude but free and useful for tracking

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u/baseline_drifteranalytical1 point·1 year ago

eGFR noise on rapid loss is real. 12 week noise, 38 week trend. Do not panic at week 64.

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u/pavel_nkemeluOP1 point·1 year ago

Baseline fasting insulin: 97.9. Week 29: 97.4. Same lab, fasted, same time of day. Trend matters.

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[deleted]1 point·1 year ago

[deleted]

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u/lina_falk0 points·1 year ago

What are your reference ranges?

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u/a1c_arcMOD174 points·1 year ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/blank_injection48 points·1 year ago

Flair changed to match the content.

Yes, exactly this, and it is the bit that took me 17 weeks to accept.

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u/intent_to_treat56 points·1 year ago

ApoB over LDL-C, that is the hierarchy

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u/lina_almeida40 points·1 year ago

You have restated the marketing copy. What is the actual substance here.

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u/pavel_nkemeluOP18 points·1 year ago

HOMA-IR is crude but free and useful for tracking

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u/cardio_endpoint_c82 points·1 year ago

eGFR noise during rapid loss is expected

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u/yara_boateng21 points·1 year ago

Small correction: the trial was 16 weeks, not 39. Does not change your point but people will quote it.

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u/nnt_nate150 points·1 year ago

Do you have baseline to compare to?

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u/diego_almeida90 points·1 year ago

This is correct. ApoB is the better marker.

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u/karl_fischer_kev56 points·1 year ago

redact identifying details from lab PDFs before posting

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u/baseline_drifteranalytical29 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/cormac_roos42 points·1 year ago

the 17 month eGFR check is the routine

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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