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c/bloodwork·submitted 2 years ago by u/diego_almeida

week 56 check-in — 22kg down, muscle cramps manageable, one thing confusing me

Baselinebranch of 6 comments

Trying to settle this properly because the thread from last year went in circles. The claim: bloodwork matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 22 months without either producing anything. What would actually settle it is 21 people measuring the same…

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6 comments, started 2 years ago
u/karl_fischer_kev205 points·2 years ago

This is correct. ApoB is the better marker.

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u/liver_enzyme_liz139 points·2 years ago

eGFR noise on rapid loss is real. 16 week noise, 4 week trend. Do not panic at week 5.

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u/kaia_kuusela93 points·2 years ago

Yeah, baseline matters more than any later number.

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u/diego_almeidaOP51 points·2 years ago

My ALT went from 15 to 18 in 63 weeks. The eGFR story shows up in the trend, not the single number.

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u/employer_carveout62 points·2 years ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/edit_for_clarity34 points·2 years ago

ApoB over LDL-C, that is the hierarchy

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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