[Question] how do you actually verify ALT
Trying to settle this properly because the thread from last year went in circles.
The claim: bloodwork matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 9 months without either producing anything.
What would actually settle it is 11 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.
If you have data, post the data. If you have an opinion, flair it as an opinion.
best — the order this archive was captured in
Mechanistically the bit that matters is ALT. It explains most of the early profile and a decent chunk of the outcome.
Respectfully this is a sample of one presented as a finding.
This is correct. ApoB is the better marker.
eGFR noise during rapid loss is expected
ALT is where the fatty-liver story shows up first
The confident tone is doing a lot of work that the evidence is not.
Respectfully this is a sample of one presented as a finding.
Retitled to remove editorialising. Put the evidence in the body.
My fasting insulin went from 14 to 37 in 44 weeks. The eGFR story shows up in the trend, not the single number.
Ferritin tanked from 10 to 9. Small appetite, reduced iron intake, nobody was testing it until I asked.
ALT is where the fatty-liver story shows up first
Ferritin tanked from 10 to 9.
Disagree on that part. 98.4% and 98.3% on the same vial is normal.
Strongly agree. ALT is where you catch the liver story early.
eGFR noise during rapid loss is expected
Retitled to remove editorialising.
Yes, exactly this, and it is the bit that took me 57 weeks to accept.
eGFR from 13 to 15 is movement, not noise
I am going to push back on this slightly.
baseline is the most important ferritin measurement, you cannot collect it later
My hs-CRP went from 11 to 14 in 57 weeks. The ALT story shows up in the trend, not the single number.
This is correct. ApoB is the better marker.
post reference ranges with your numbers, units differ by country and lab
- 1Retitled to remove editorialising. Put the evidence in the body.16 comments in this branch · started by u/liver_enzyme_liz
- 2Mechanistically the bit that matters is ALT. It explains most of the early…4 comments in this branch · started by u/britt_marchand