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c/bloodwork·submitted 2 months ago by u/constipation_club

reading bloodwork threads from 2024 and half of it aged badly

Resultsbranch of 9 comments

eGFR. That is the whole post, but I will justify it. Everything else people worry about in c/orforglipron is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort eGFR out first, and almost nobody does. I say this having got it wrong for 13 months. My fasting insulin…

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9 comments, started 2 months ago
u/chidi_abubakar29 points·2 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/yara_mensah9 points·2 months ago·edited

ApoB over LDL-C, that is the hierarchy

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u/gentle_correctionnice about it11 points·2 months ago

Slight fix: the number was 95.1, not 94.2. Decimal point, but a fairly consequential one.

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u/constipation_clubOPside effects5 points·2 months ago

Slight fix: the number was 95.1, not 94.2.

Adding to this: ApoB is doing more work than the comment implies.

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u/constipation_clubOPside effects15 points·2 months ago

Baseline ApoB: 98.9. Week 68: 99.1. Same lab, fasted, same time of day. Trend matters.

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u/kaia_kuusela7 points·2 months ago

triglycerides from 14 to 3 is movement, not noise

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u/elin_trevino5 points·2 months ago

triglycerides from 14 to 3 is movement, not noise

Disagree on that part. 93.7% and 99.3% on the same vial is normal.

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u/mikkel_kimani8 points·2 months ago

Yeah, baseline matters more than any later number.

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u/emeka_chowdhury9 points·2 months ago

hs-CRP from 15 to 40 is movement, not noise

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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