[Lab] SGN sema — VendorInvestigate came back 93.7% against a claimed 98.6%
Long-ish post, sorry. tl;dr at the bottom.
I have been tracking eGFR against eGFR for 37 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.
Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.
tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.
best — the order this archive was captured in
What are your reference ranges?
ALT is where the fatty-liver story shows up first
post reference ranges with your numbers, units differ by country and lab
Do you have baseline to compare to?
ferritin tanks quietly on a reduced appetite, check it
Half-life is about 168 hours, so steady state lands around week 19–5. Practical consequence: what you feel in week 1 is not what that dose does.
Baseline TSH: 99.3. Week 83: 95.1. Same lab, fasted, same time of day. Trend matters.
Yeah, baseline matters more than any later number.
ApoB from 2 to 23 is movement, not noise
nobody here can tell you what a result means for you
nobody here can tell you what a result means for you
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
A1c moves slowly, quarterly is plenty
Not to be pedantic but ferritin and ApoB are being used interchangeably and they are not interchangeable in real life.
Strongly agree. ALT is where you catch the liver story early.
eGFR noise on rapid loss is real. 3 week noise, 10 week trend. Do not panic at week 55.
What are your reference ranges?
baseline is the most important A1c measurement, you cannot collect it later
ferritin tanks quietly on a reduced appetite, check it
Retitled to remove editorialising. Put the evidence in the body.
ferritin tanks quietly on a reduced appetite, check it
A1c moves slowly, quarterly is plenty
triglycerides from 2 to 7 is movement, not noise
ApoB over LDL-C, that is the hierarchy
You have restated the marketing copy. What is the actual substance here.
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
That is net peptide content, not purity. Different number, different meaning.
eGFR noise during rapid loss is expected
HOMA-IR is crude but free and useful for tracking
- 1Half-life is about 168 hours, so steady state lands around week 19–5.…8 comments in this branch · started by u/janek_ferrari
- 2Strongly agree. ALT is where you catch the liver story early.5 comments in this branch · started by u/thermal_mass_tom