[Question] how do you actually verify amylin
Been lurking in c/orforglipron for about 18 months and finally have something worth posting. Short version: week 28, 12.5mg, and amylin is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 5 threads, and the answers split roughly down the middle. What I actually want to know…
This is correct. The co-agonism is real.
The confident tone is doing a lot of work that the evidence is not.
the mechanism is different, the side effect profile reflects it
The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does CagriSema.
the amylin agonist pool is small, community is satiety
long-acting amylin is REDEFINE, different satiety profile