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c/glp1muscle·posted 1 year ago by u/rina_nascimento

small win: sarcopenia stopped being a problem at week 31

Discussion Clean Column ×8

Confession thread, sort of.

I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 23 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.

So now I have sulphur burps I did not need and a data point I cannot interpret. Two lessons in one.

Posting it in the hope that somebody at week 48 reads it before doing the same thing.

856 up / 245 down78% upvoted24 commentsid 54xtot17 Jun 2025

24 comments

21 in this archive, depth 4

best — the order this archive was captured in

u/rasmus_petrescu72 points·1 year ago

DEXA is the real measurement

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u/rina_nascimentoOP31 points·1 year ago

The injection-site soreness was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/joaquin_trevino-4 points·1 year ago

protein sarcopenia, not "lots"

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u/constipation_clubside effects1 point·1 year ago

Genuine question — what concentration were you at?

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u/maren_ibarra43 points·1 year ago

lean mass retention is the 39 week conversation

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u/yannick_haddad15 points·1 year ago·edited

FFMI tracking requires body composition

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u/cold_chromatogram_only38 points·1 year ago·edited

Yeah, protein matters on rapid loss.

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u/mikkel_correia12 points·1 year ago·edited

bathroom BIA scales are not a method

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u/annika_fonseca5 points·1 year ago

sarcopenia is the unsolved question

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u/joaquin_wojcik33 points·1 year ago

You have restated the marketing copy. What is the actual substance here.

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u/rina_nascimentoOP27 points·1 year ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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u/prior_auth_painappeals21 points·1 year ago

Slight fix: the number was 95.1, not 94.2. Decimal point, but a fairly consequential one.

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u/joaquin_trevino7 points·1 year ago

Respectfully this is a sample of one presented as a finding.

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u/adaeze_cabrera3 points·1 year ago

protein DEXA, not "lots"

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u/nikhil_asante15 points·1 year ago

Small correction: the trial was 19 weeks, not 30. Does not change your point but people will quote it.

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[deleted]7 points·1 year ago

[deleted]

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u/lina_bruun26 points·1 year ago·edited

Yeah, protein matters on rapid loss.

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u/sunday_shot_sal25 points·1 year ago

I am going to push back on this slightly.

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u/rina_nascimentoOP9 points·1 year ago

lean mass retention is the 68 week conversation

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u/baseline_drifteranalytical3 points·1 year ago

protein targets in g/kg

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u/TitrationTortoiseslow and boring35 points·1 year ago

This is correct. DEXA is the standard.

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About c/glp1muscle

Lean-mass retention during rapid weight loss: protein targets, resistance-training minimums, DEXA and BIA measurement reality, FFMI tracking, and the sarcopenia question that nobody funded a proper trial for.

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  1. Body-composition claims need a method. Bathroom BIA scales are not a method.
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