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c/orforglipron·submitted 2 months ago by u/dario_boateng

does orforglipron actually matter or is it forum lore at this point

Discussionbranch of 9 comments

I have had 9 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 18 days on nominally the same lane, which matters more in summer than in February. The independent number came back 97.9% against a claimed…

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9 comments, started 2 months ago
u/nils_ferreira24 points·2 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/quiet_moderatormod7 points·2 months ago

the absorption problem is solved by non-peptide structure

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u/sofia_petrescu7 points·2 months ago

Came off after 95 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/aksel_kjaer2 points·2 months ago·edited

This is correct. ATTAIN data is phase 13.

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u/soren_yildiz0 points·2 months ago

availability speculation must be flaired Speculation

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u/ice_pack_auditcold chain11 points·2 months ago

What was the batch number and which service?

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u/hazard_ratio_halstats4 points·2 months ago·edited

the nausea profile is speculative at this stage

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u/incretin_ivypharmacology4 points·2 months ago·edited

phase 22 data is interesting, phase 16 will tell the real story

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u/chidi_yilmaz1 point·2 months ago

availability speculation must be flaired Speculation

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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