GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of [Question] New Zealand — has anyone got a straight answer on non-peptide — 69 comments in the full submission. View in context.
1.2k
c/orforglipron·submitted 1 year ago by u/hamza_weiss

[Question] New Zealand — has anyone got a straight answer on non-peptide

Questionbranch of 14 comments

Trying to settle this properly because the thread from last year went in circles. The claim: small molecule matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 10 months without either producing anything. What would actually settle it is 5 people measuring the…

Read the full submission and all 69 comments →

This branch

14 comments, started 1 year ago
u/cloudy_vial_carol28 points·1 year ago

What was the batch number and which service?

replysharereportpermalink
u/marit_sandvik22 points·1 year ago·edited

oral non-peptide agonist is ACHIEVE, no food restrictions

replysharereportpermalink
u/viktor_laurent9 points·1 year ago

availability speculation must be flaired Speculation

replysharereportpermalink
u/emil_agyeman3 points·1 year ago

How many weeks between the two measurements?

replysharereportpermalink
[removed]2 points·1 year ago

[removed by moderator]

replysharereportpermalink
u/hamza_weiss17 points·1 year ago

the muscle cramps profile is speculative at this stage

replysharereportpermalink
u/ayesha_erdogan12 points·1 year ago

Small correction: the trial was 17 weeks, not 15. Does not change your point but people will quote it.

replysharereportpermalink
u/aksel_kjaer23 points·1 year ago·edited

The constipation was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

replysharereportpermalink
u/hamza_weissOP10 points·1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

replysharereportpermalink
u/hamza_weissOP18 points·1 year ago

Stalled for 21 weeks, changed nothing, and it started moving again on week 62.

replysharereportpermalink
u/throwaway_wl202618 points·1 year ago

Titration speed is a side-effect dial far more than an efficacy dial.

replysharereportpermalink
u/salma_almeida9 points·1 year ago

the supply conversation changes if this approves

replysharereportpermalink
u/certified_referenceQC4 points·1 year ago

ATTAIN and ACHIEVE are phase 16 trials

replysharereportpermalink
u/tomas_lundgren2 points·1 year ago

ATTAIN and ACHIEVE are phase 16 trials

Adding to this: non-peptide is doing more work than the comment implies.

replysharereportpermalink

← back to the whole thread

About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

21kmembers
62submissions
Feb 2024created
submissions / month, last year
Sponsored

Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

janoshik.com
Sponsored

GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

glbiochem.net
c/orforglipron rules
  1. Small molecule, not a peptide. Purity discussion here is a different problem.
  2. Cite ATTAIN/ACHIEVE arms specifically when quoting numbers.
  3. Availability speculation must be flaired Speculation.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Moderators
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.