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c/orforglipron·submitted 1 year ago by u/ines_lindqvist

oral GLP-1 is the most under-discussed thing in c/darkspot

Speculationbranch of 7 comments

ACHIEVE. That is the whole post, but I will justify it. Everything else people worry about in c/survodutide is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort ACHIEVE out first, and almost nobody does. I say this having got it wrong for 5 months. My ApoB was the…

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7 comments, started 1 year ago
u/aksel_kjaer2 points·1 year ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/cato_batista2 points·1 year ago

Strongly agree. The supply impact would be huge.

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u/scam_taxonomyc/scamalerts1 point·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/flair_enthusiast1 point·1 year ago

oral non-peptide agonist is small molecule, no food restrictions

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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