GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of someone explain small molecule to me like I have not read a paper in years — 51 comments in the full submission. View in context.
2.4k
c/orforglipron·submitted 9 months ago by u/lina_novak

someone explain small molecule to me like I have not read a paper in years

Trial Databranch of 5 comments

ACHIEVE. That is the whole post, but I will justify it. Everything else people worry about in c/survodutide is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort ACHIEVE out first, and almost nobody does. I say this having got it wrong for 20 months. My…

Read the full submission and all 51 comments →

This branch

5 comments, started 9 months ago
u/soren_yildiz66 points·9 months ago

ATTAIN and ACHIEVE are phase 10 trials

replysharereportpermalink
u/lina_novak24 points·9 months ago

What are you comparing it against though?

replysharereportpermalink
u/soren_yildiz14 points·9 months ago

oral non-peptide agonist is ACHIEVE, no food restrictions

replysharereportpermalink
u/marit_laurent35 points·9 months ago

the fatigue profile is speculative at this stage

replysharereportpermalink
u/ines_lindqvist19 points·9 months ago·edited

Has anyone actually got this in writing, or is it forum lore at this point?

replysharereportpermalink

← back to the whole thread

About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

21kmembers
62submissions
Feb 2024created
submissions / month, last year
Sponsored

Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

janoshik.comSponsored

GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

glbiochem.net
More in c/orforglipron
c/orforglipron rules
  1. Small molecule, not a peptide. Purity discussion here is a different problem.
  2. Cite ATTAIN/ACHIEVE arms specifically when quoting numbers.
  3. Availability speculation must be flaired Speculation.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/incretin_ivyu/phase_two_peteu/trialwatch_theo
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →