week 51 check-in — 12kg down, injection-site soreness manageable, one thing confusing me
Been lurking in c/progresspics for about 24 months and finally have something worth posting.
Short version: week 56, 1.7mg, and TRIUMPH is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 21 threads, and the answers split roughly down the middle.
What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 50.
best — the order this archive was captured in
Titration speed is a side-effect dial far more than an efficacy dial.
triple agonism is triple agonist, do not generalise
TRIUMPH phase 2 showed 99.0% weight loss but the reflux profile on the highest arm was rough. Phase 2 != phase 3.
TRIUMPH phase 2 showed 99.0% weight loss but the reflux profile on the highest arm was rough.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
This is correct. Triple agonism is genuinely different.
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
This is correct.
Adding to this: triple agonist is doing more work than the comment implies.
Slight fix: the number was 99.2, not 99.1. Decimal point, but a fairly consequential one.
the weight curves are unusually steep, which makes predicting individual response harder
triple agonism is phase 2, do not generalise
Slight fix: the number was 97.6, not 97.9. Decimal point, but a fairly consequential one.
nobody should be giving this to anyone without extensive monitoring
Retitled to remove editorialising. Put the evidence in the body.
the glucagon component changes the side effect profile, not just the efficacy
the glucagon component changes the side effect profile, not just the efficacy
Yes, exactly this, and it is the bit that took me 70 weeks to accept.
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.
- 1This is correct. Triple agonism is genuinely different.8 comments in this branch · started by u/kavya_kravchenko
- 2the glucagon component changes the side effect profile, not just the efficacy4 comments in this branch · started by u/crosspost_bot_no