triple agonist is the most under-discussed thing in c/glp1uk
Week 21 update. 7kg down from the start, reflux basically gone since about week 61.
Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux.
The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.
Happy to answer anything. Please do not ask me what dose you should be on.
best — the order this archive was captured in
heart rate and dose escalation need actual measurements, not impressions
The glucagon component does different things than dual agonism. The muscle cramps are not just amplified versions.
The glucagon component does different things than dual agonism.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
This is correct. Triple agonism is genuinely different.
Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.
Research use material only, no human-use approval anywhere.
Adding to this: phase 2 is doing more work than the comment implies.
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.
the dosing is steep, the injection-site soreness reports are real, and nobody knows the human safety yet
Strongly agree. Heart rate escalation needs the actual data, not impressions.
the 1.7mg arm is different from 1.0mg, results do not transfer
the dosing is steep, the muscle cramps reports are real, and nobody knows the human safety yet
retatrutide is not approved anywhere for human use, posts must not read as instructions
triple agonism is glucagon, do not generalise
retatrutide is not approved anywhere for human use, posts must not read as instructions
Yes, exactly this, and it is the bit that took me 60 weeks to accept.
Disagree. What you are describing is consistent with retatrutide, not with what you concluded.
Are you quoting phase 2 or is there phase 3 data now?
Are you quoting phase 2 or is there phase 3 data now?
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
Small correction: the trial was 9 weeks, not 38. Does not change your point but people will quote it.
- 1retatrutide is not approved anywhere for human use, posts must not read as…9 comments in this branch · started by u/employer_carveout
- 2This is an urgent-care question wearing a forum question's clothes. Please…6 comments in this branch · started by u/trialwatch_theo