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c/retatrutide·submitted 9 months ago by u/ewan_zielinski

22 months in and triple agonist is still the thing I get wrong

Cautionbranch of 7 comments

Trying to settle this properly because the thread from last year went in circles. The claim: glucagon matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 23 months without either producing anything. What would actually settle it is 31 people measuring the same…

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7 comments, started 9 months ago
u/reflux_report31 points·9 months ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/signe_villalobos9 points·9 months ago

Did you actually measure heart rate or is that a feeling?

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u/rosa_almeida2 points·9 months ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/crosspost_bot_no3 points·9 months ago

research use only, handling and analysis, not protocols

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u/marta_vanhecke2 points·9 months ago

research use only, handling and analysis, not protocols

Adding to this: dose escalation is doing more work than the comment implies.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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