GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of is it normal to get fatigue at week 90 — 50 comments in the full submission. View in context.
4.5k
c/retatrutide·submitted 9 months ago by u/injection_site_iris

is it normal to get fatigue at week 90

Discussionbranch of 7 comments

Quick one. Canada here. glucagon works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 20 weeks and cost roughly what I expected. The admin was worse than the…

Read the full submission and all 50 comments →

This branch

7 comments, started 9 months ago
u/baseline_drifteranalytical176 points·9 months ago·edited

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

replysharereportpermalink
u/ledger_modmod · vetting58 points·9 months ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

replysharereportpermalink
u/careful_gradient_again112 points·9 months ago

triple agonism is glucagon, do not generalise

replysharereportpermalink
u/ferran_krastev163 points·9 months ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

replysharereportpermalink
u/injection_site_irisOP47 points·9 months ago

I am going to push back on this slightly.

replysharereportpermalink
u/hugo_pires59 points·9 months ago

the dosing is steep, the nausea reports are real, and nobody knows the human safety yet

replysharereportpermalink
u/hassan_nilsen17 points·9 months ago·edited

Strongly agree. Heart rate escalation needs the actual data, not impressions.

replysharereportpermalink

← back to the whole thread

About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

65kmembers
130submissions
Sep 2023created
submissions / month, last year
Sponsored

Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

janoshik.comSponsored

GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

glbiochem.net
More in c/retatrutide
c/retatrutide rules
  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/reta_and_regretu/trialwatch_theou/incretin_ivyu/ledger_mod
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →