does glucagon actually matter or is it forum lore at this point
Something I noticed reading old threads that I have not seen said out loud. The advice on TRIUMPH in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with…
the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet
the weight curves are unusually steep, which makes predicting individual response harder
the weight curves are unusually steep, which makes predicting individual response harder
Adding to this: TRIUMPH is doing more work than the comment implies.
the glucagon component changes the side effect profile, not just the efficacy
Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.
the dosing is steep, the constipation reports are real, and nobody knows the human safety yet
TRIUMPH data is phase 2, not phase 3, smaller n and shorter