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c/retatrutide·posted 1 year ago by u/solene_ilunga

[Meta] proposal — a flair for glucagon posts

Caution Cold Box ×3 The Quiet One ×1 Receipts ×2

I have had 5 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 24 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 97.9% against a claimed 98.0%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

5,920 up / 936 down86% upvoted30 commentsid h2thfu12 Aug 2024

30 comments

23 in this archive, depth 5

best — the order this archive was captured in

u/matias_falk769 points·1 year ago

What was the dosing schedule in that arm?

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u/andres_sorensen475 points·1 year ago
post the spreadsheet
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u/reta_and_regretMOD251 points·1 year ago

Tracking number removed. It identifies both ends of a shipment.

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u/emil_wojcik79 points·1 year ago·edited

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/clara_weiss404 points·1 year ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/soren_nkemelu295 points·1 year ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/blunt_coldbox_2024401 points·1 year ago

What was the dosing schedule in that arm?

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[deleted]126 points·1 year ago

[deleted]

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u/solene_ilungaOP216 points·1 year ago

triple agonism is phase 2, do not generalise

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u/divya_bakken-7 points·1 year ago

retatrutide is not approved anywhere for human use, posts must not read as instructions

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u/titration_marshalmod · c/semaglutide176 points·1 year ago·edited

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/sofia_wikstrom210 points·1 year ago

nobody should be giving this to anyone without extensive monitoring

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u/injection_site_iris110 points·1 year ago

the weight curves are unusually steep, which makes predicting individual response harder

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u/emil_agyeman69 points·1 year ago·edited

triple agonism is phase 2, do not generalise

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/quiet_moderatormod138 points·1 year ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/isabela_nilsen93 points·1 year ago

Which trial arm and what was the n?

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u/two_mil_or_one23 points·1 year ago

Did you actually measure heart rate or is that a feeling?

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u/careful_gradient_notes18 points·1 year ago

the weight curves are unusually steep, which makes predicting individual response harder

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u/nadia_trevino8 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/lurker_for_years64 points·1 year ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/signe_villalobos41 points·1 year ago

Strongly agree.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/ewan_marchand90 points·1 year ago

research use only, handling and analysis, not protocols

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u/endotoxin_elliemicro35 points·1 year ago

research use only, handling and analysis, not protocols

Disagree on that part. 98.1% and 98.3% on the same vial is normal.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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c/retatrutide rules
  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
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