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c/retatrutide·submitted 23 days ago by u/trialwatch_theo

[PSA] dose escalation is not what most of this community thinks it is

Discussionbranch of 7 comments

Right, the triple agonist question again, but with numbers this time. I have 24 data points over 22 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

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7 comments, started 22 days ago
u/quiet_moderatormod127 points·22 days ago

the 12.5mg arm is different from 15mg, results do not transfer

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u/marta_vanhecke-26 points·21 days ago

triple agonism is phase 2, do not generalise

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u/discount_math_dm1 point·21 days ago

triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual

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u/isabela_nilsen1 point·21 days ago

Which trial arm and what was the n?

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u/trialwatch_theoOPtrial nerd1 point·21 days ago

nobody should be giving this to anyone without extensive monitoring

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[removed]1 point·21 days ago

[removed by moderator]

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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