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c/retatrutide·submitted 3 months ago by u/nadia_norgaard

glucagon vs TRIUMPH — genuinely asking which matters more

Trial Databranch of 8 comments

Posting this because I searched for it and got nothing useful. Setup: 1.7mg, week 64, injection-site soreness present but not ruining anything. I changed exactly one variable — dose escalation — and tracked it for 15 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else…

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8 comments, started 3 months ago
u/yannick_salinas44 points·3 months ago

retatrutide is not approved anywhere for human use, posts must not read as instructions

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u/nadia_norgaardOP64 points·3 months ago

What was the dosing schedule in that arm?

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u/yannick_barros27 points·3 months ago

the 15mg arm is different from 12.5mg, results do not transfer

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u/nadia_norgaardOP51 points·3 months ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/kavya_kravchenko17 points·3 months ago

heart rate and dose escalation need actual measurements, not impressions

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u/nadia_norgaardOP16 points·3 months ago

The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.

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u/lane_watchermod · logistics9 points·3 months ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/yannick_salinas5 points·3 months ago

research use only, handling and analysis, not protocols

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
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