glucagon vs TRIUMPH — genuinely asking which matters more
Posting this because I searched for it and got nothing useful.
Setup: 1.7mg, week 64, injection-site soreness present but not ruining anything. I changed exactly one variable — dose escalation — and tracked it for 15 weeks.
Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.
Not medical advice, obviously. This is one person with a spreadsheet.
best — the order this archive was captured in
Which trial arm and what was the n?
the glucagon component changes the side effect profile, not just the efficacy
Strongly agree. Heart rate escalation needs the actual data, not impressions.
the weight curves are unusually steep, which makes predicting individual response harder
Disagree but this is the good kind of wrong — it is specific enough to be checked.
phase 2 numbers are not maintenance numbers, cite the trial
Did you actually measure heart rate or is that a feeling?
the dosing is steep, the injection-site soreness reports are real, and nobody knows the human safety yet
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
Which trial arm and what was the n?
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
retatrutide is not approved anywhere for human use, posts must not read as instructions
What was the dosing schedule in that arm?
the 15mg arm is different from 12.5mg, results do not transfer
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
heart rate and dose escalation need actual measurements, not impressions
The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.
Strongly agree. Heart rate escalation needs the actual data, not impressions.
research use only, handling and analysis, not protocols
- 1Which trial arm and what was the n?10 comments in this branch · started by u/cold_chromatogram_only
- 2retatrutide is not approved anywhere for human use, posts must not read as…8 comments in this branch · started by u/yannick_salinas