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c/survodutide·submitted 21 days ago by u/yannick_petrov

[Results] 42 weeks, 31kg, and dual agonist was the hard part

Cautionbranch of 7 comments

Quick one. Canada here. MASH works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 15 weeks and cost roughly what I expected. The admin was worse than the cost.…

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7 comments, started 20 days ago
u/certified_referenceQC10 points·20 days ago

Came off after 26 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/yannick_petrovOP4 points·19 days ago

Respectfully this is a sample of one presented as a finding.

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[removed]3 points·19 days ago

[removed by moderator]

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u/annika_fonseca2 points·19 days ago

do not generalise from tirzepatide

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u/milos_mensa1 point·19 days ago

MASH claims need the trial and the biopsy endpoint

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u/elin_ferrari2 points·19 days ago

the GLP-1/glucagon dual is hepatic fat, different from GIP/GLP-1

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u/britt_okwuosa1 point·18 days ago·edited

the GLP-1/glucagon dual is hepatic fat, different from GIP/GLP-1

Disagree on that part. 98.4% and 98.3% on the same vial is normal.

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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