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c/tapering·posted 5 days ago by u/janek_ferrari

[Results] came off deliberately over four months, regained 4kg not 24

Results Cold Box ×9

Trying to settle this properly because the thread from last year went in circles.

The claim: discontinuation matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 23 months without either producing anything.

What would actually settle it is 13 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.

If you have data, post the data. If you have an opinion, flair it as an opinion.

403 up / 68 down86% upvoted28 commentsid rstcjg24 Jul 2026

28 comments

22 in this archive, depth 3

best — the order this archive was captured in

u/taper_off_tabitha0 points·4 days ago
yep. 90 weeks in, same.
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u/dario_stanescu35 points·5 days ago

Respectfully this is a sample of one presented as a finding.

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u/janek_ferrariOP16 points·5 days ago

This is correct. Discontinuation data is real.

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u/vikram_ferreira42 points·5 days ago

the 5 week discontinuation arm is the data

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[deleted]16 points·5 days ago

[deleted]

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u/neha_krastev21 points·4 days ago

coming off deliberately, not by accident

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u/TitrationTortoiseslow and boring35 points·5 days ago

the 5 week discontinuation arm is the data

Yes, exactly this, and it is the bit that took me 3 weeks to accept.

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u/liv_kuipers21 points·3 days ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/maren_baptista27 points·3 days ago

say how long you were on and at what dose before taper

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u/elin_varga9 points·3 days ago

Small correction: the trial was 13 weeks, not 18. Does not change your point but people will quote it.

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u/customs_seizure_sid12 points·4 days ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/chain_confirm_cpayments9 points·4 days ago

You have restated the marketing copy. What is the actual substance here.

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u/ahmed_okafor12 points·3 days ago

Yeah, regain is not a failure.

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u/lina_adebayo8 points·5 days ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/maintenance_mode_maxMOD6 points·4 days ago

Tracking number removed. It identifies both ends of a shipment.

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u/coldchain_karencold chain2 points·4 days ago

Which country? Half the answers in this thread only apply in France.

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u/peptidemeter_pat5 points·5 days ago

tapering instructions are not welcome here

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u/cormac_roos4 points·4 days ago

the people who came off and restarted without shame

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u/anders_kuusela3 points·5 days ago·edited

Strongly agree. The regain is expected.

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u/rina_bergstrom5 points·3 days ago

tapering instructions are not welcome here

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u/cormac_erdogan4 points·4 days ago
this deserves more than 10 upvotes
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u/customs_seizure_sid3 points·4 days ago

This is correct. Discontinuation data is real.

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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