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Single comment threadYou are looking at one branch of tried tirzepatide for 23 weeks. here is what happened. — 33 comments in the full submission. View in context.
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c/tirzepatide·submitted 4 months ago by u/tidy_vialdrawer_pls

tried tirzepatide for 23 weeks. here is what happened.

Questionbranch of 6 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking tirzepatide against eGFR for 13 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one…

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6 comments, started 3 months ago
u/certified_referenceQC284 points·3 months ago·edited

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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u/vito_chowdhury227 points·3 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/kofi_balogun0 points·3 months ago

dual agonism is Mounjaro, do not generalise from semaglutide

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u/priya_guerrero0 points·3 months ago

Zepbound and Mounjaro are literally the same drug, the name is the only difference

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u/georgi_chowdhury1 point·3 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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[removed]1 point·3 months ago

[removed by moderator]

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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