Right, the discontinuation question again, but with numbers this time. I have 8 data points over 32 weeks. The pattern is consistent enough that I do not think it is…
u/coldchain_karen
I own four data loggers and I will lend you one. Excursions are survivable; ignorance is not.
long-standing contributor · cold chain · joined 5 Sep 2023
Overview — page 4 of 5
comment on tried excursion for 2 weeks. here is what happened. in c/coldchain · 11 points · 1 year ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on [Results] 16 weeks on 7.5mg, full numbers, ask me anything boring in c/bloodwork · 222 points · 1 year ago
comment on switched from 0.25mg to 1.7mg and the early fullness got better, not worse in c/coldchain · 435 points · 1 year ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on small win: tapering stopped being a problem at week 30 in c/tapering · 17 points · 1 year ago
STEP 1 and SURMOUNT-4 discontinuation arms show regain
comment on [Results] 66 weeks on 10mg, full numbers, ask me anything boring in c/coldchain · 14 points · 1 year ago
no tracking numbers, no full addresses, no label photos — instant removal
comment on [Results] 66 weeks on 10mg, full numbers, ask me anything boring in c/coldchain · 337 points · 1 year ago
lyophilised powder is far more forgiving than reconstituted solution
Disagree on that part. 99.2% and 99.3% on the same vial is normal.
comment on [Results] 66 weeks on 10mg, full numbers, ask me anything boring in c/coldchain · 104 points · 1 year ago
Tracking number removed. It identifies both ends of a shipment.
comment on stalled for 8 weeks at 12.5mg and I refuse to panic this time in c/bloodwork · 20 points · 1 year ago
Small correction: the trial was 18 weeks, not 28. Does not change your point but people will quote it.
comment on am I the only one who found cold chain harder than the injections in c/coldchain · 56 points · 1 year ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on [Meta] proposal — a flair for eGFR posts in c/bloodwork · 1 points · 1 year ago
nobody here can tell you what a result means for you
comment on is it normal to get nausea at week 30 in c/coldchain · 235 points · 1 year ago
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
comment on lyophilised vs stability — genuinely asking which matters more in c/coldchain · 623 points · 1 year ago
Logger trace from my shipment: 10 hours at 31°C. Powder tested 99.3% against 93.7% claim. Tolerates more than the box implies.
comment on why does nobody talk about lipids in c/bloodwork · -27 points · 1 year ago
Yeah, baseline matters more than any later number.
comment on help me understand appetite return, I have read the wiki twice in c/tapering · 42 points · 1 year ago
Yeah, regain is not a failure.
Adding to this: appetite return is doing more work than the comment implies.
comment on anyone else notice discontinuation kicking in around week 29 in c/tapering · 8 points · 1 year ago
This is correct. Discontinuation data is real.
comment on [Vendor] WXT order #7 — the Netherlands, 3 days, no drama, receipts inside in c/tapering · 32 points · 2 years ago
Stalled for 18 weeks, changed nothing, and it started moving again on week 66.
comment on [Vendor] WXT order #7 — the Netherlands, 3 days, no drama, receipts inside in c/tapering · 46 points · 2 years ago
Maintenance for 24 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.
comment on [Vendor] WXT order #7 — the Netherlands, 3 days, no drama, receipts inside in c/tapering · 59 points · 2 years ago
coming off deliberately, not by accident
comment on my triglycerides moved and I cannot work out whether ferritin is why in c/bloodwork · 69 points · 2 years ago
ApoB over LDL-C, that is the hierarchy