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JO

u/joaquin_trevino

Contributes reviews on supplier material. Based in Coimbra.

member · joined 16 Jul 2025

16,733post karma
6,285comment karma
10submissions
141comments

comment on [Stats] relative risk reduction sells papers, absolute risk reduction makes decisions in c/trialwatch · 14 points · 2 days ago

Yeah, absolute numbers matter more than the press release.

Adding to this: SURMOUNT is doing more work than the comment implies.

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comment on [Paper] SURMOUNT-4 withdrawal arm, read the appendix not the abstract in c/trialwatch · 1 points · 3 days ago

The confident tone is doing a lot of work that the evidence is not.

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comment on [Question] cycle got longer by six days. anyone else. in c/glp1women · -26 points · 3 days ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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comment on [Log] week 78, dose, weight, waist, sides, labs. nothing hidden. in c/dosinglogs · 1 points · 3 days ago

Small correction: the trial was 17 weeks, not 9.

Adding to this: tracking is doing more work than the comment implies.

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comment on [Explainer] why "compounded" does not mean "generic" in c/compounding · 25 points · 4 days ago

shortage list status is telehealth, check the actual list

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comment on [Caution] trying to conceive? that is a clinician conversation, not a forum one in c/glp1women · 13 points · 5 days ago

Strongly agree. Cycle changes are documented.

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comment on [Press Release] new phase 3 numbers, no publication yet, calm down in c/trialwatch · 9 points · 7 days ago

yep. 9 weeks in, same.

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comment on [Results] perimenopause, 18 months, and why the usual advice failed me in c/glp1women · 6 points · 8 days ago

Yeah, insulin resistance is under-researched.

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comment on [Discussion] the weight conversation drowns out the glycaemic one in c/t2dglp1 · 6 points · 11 days ago

Week 13 for me and the honest summary is: 36kg down, the food-noise thing manageable, and I have thought about food maybe four times today.

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comment on [Discussion] the compounding gap was a symptom, not a solution in c/compounding · 14 points · 11 days ago

API transparency is the question that separates good compounders from sketchy ones

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comment on [Data] BIA vs DEXA on the same day, 6% apart, pick a method and stay with it in c/glp1muscle · 1 points · 11 days ago

This is correct. DEXA is the standard.

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comment on [Discussion] the weight conversation drowns out the glycaemic one in c/t2dglp1 · 8 points · 12 days ago

Week 26 for me and the honest summary is: 44kg down, reflux manageable, and I have thought about food maybe four times today.

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comment on intent-to-treat vs per-protocol explains half the arguments on this site in c/trialwatch · 21 points · 13 days ago

Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.

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comment on [Paper] ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggests in c/trialwatch · 8 points · 15 days ago

Strongly agree. Phase 2 is investigational, not conclusive.

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comment on [Discussion] can we stop arguing about T2D until somebody posts a number in c/t2dglp1 · 2 points · 17 days ago

Strongly agree. A1c matters as much as weight.

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comment on [Lab] my running table: 34 tests, 11 vendors, three years in c/labresults · 1 points · 19 days ago

Which Medutest service and what method did they use?

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comment on [Concluded] 104 weeks. final numbers. thanks for reading. in c/dosinglogs · 21 points · 19 days ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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comment on 10 months in and insulin resistance is still the thing I get wrong in c/glp1women · -7 points · 20 days ago

the cycle tracking data matters, keep it private

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comment on [Below Spec] 88% is not "basically fine" and i am tired of that reply in c/labresults · 21 points · 22 days ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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comment on [Struggle] eight weeks, 2kg, doing everything right, and it is grinding me down in c/progresspics · 1 points · 22 days ago

non-scale victories count, post them

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