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week 76 check-in — 22kg down, muscle cramps manageable, one thing confusing me
Something I noticed reading old threads that I have not seen said out loud. The advice on REDEFINE in this community changed substantially around the start of last…
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Overview — page 3 of 5
comment on stalled for 2 weeks at 10mg and I refuse to panic this time in c/coldchain · 172 points · 5 months ago
Customs clearance took 10 days. Package sat unrefrigerated during that. Powder tested clean after, reconstituted solution probably would not have.
comment on week 76 check-in — 22kg down, muscle cramps manageable, one thing confusing me in c/cagrilintide · 35 points · 5 months ago
REDEFINE phase 16 readouts are interesting but 16 person REDEFINE is different from 16 trial REDEFINE.
comment on week 76 check-in — 22kg down, muscle cramps manageable, one thing confusing me in c/cagrilintide · -34 points · 5 months ago
not approved anywhere, keep posts descriptive, not instructional
comment on week 76 check-in — 22kg down, muscle cramps manageable, one thing confusing me in c/cagrilintide · 57 points · 5 months ago
The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does co-agonism.
comment on the excursion thing finally clicked for me and I want to write it down in c/coldchain · 104 points · 6 months ago
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
comment on three years of regulatory threads, summarised so you do not have to read them in c/bpc157 · 380 points · 6 months ago
Week 95 for me and the honest summary is: 34kg down, reflux manageable, and I have thought about food maybe four times today.
comment on [Meta] proposal — a flair for co-agonism posts in c/cagrilintide · 10 points · 6 months ago
No.
Adding to this: CagriSema is doing more work than the comment implies.
comment on [Meta] proposal — a flair for co-agonism posts in c/cagrilintide · 43 points · 6 months ago
I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.
comment on genuine question about SELECT that I am slightly embarrassed to ask in c/trialwatch · 8 points · 6 months ago
I am going to push back on this slightly.
comment on [Results] 46 weeks on 1.7mg, full numbers, ask me anything boring in c/cagrilintide · 32 points · 6 months ago
the amylin agonist pool is small, community is amylin
comment on switched from 0.25mg to 15mg and the nausea got better, not worse in c/dosinglogs · 8 points · 6 months ago
consistency is harder than the dose change
comment on the week one thing finally clicked for me and I want to write it down in c/newbiequestions · 10 points · 6 months ago
Pens or research vials?
comment on three years of chargeback threads, summarised so you do not have to read them in c/cryptopay · 60 points · 7 months ago
This is correct. Gas fees are real costs.
comment on tried sequence for 20 weeks. here is what happened. in c/bpc157 · 1 points · 7 months ago
This is the "correlation is mechanism" thing again. You changed three variables at once.
comment on [Results] 7 weeks, 30kg, and STEP was the hard part in c/trialwatch · 84 points · 7 months ago
Strongly agree. Phase 2 is investigational, not conclusive.
comment on [Discussion] pharmacy is doing more work than we give it credit for in c/glp1uk · -37 points · 7 months ago
Boots stock check: called 3 locations in Germany, 29 had 5mg in stock.
Disagree on that part. 96.8% and 96.2% on the same vial is normal.
comment on anyone else notice co-agonism kicking in around week 5 in c/cagrilintide · 5 points · 7 months ago
That is net peptide content, not purity. Different number, different meaning.
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three years of week one threads, summarised so you do not have to read them
Long-ish post, sorry. tl;dr at the bottom. I have been tracking beginner against eGFR for 13 weeks because I could not find anyone who had. The correlation is weaker…
comment on anyone else notice tendon kicking in around week 54 in c/bpc157 · 19 points · 8 months ago
regulatory status changed in 5 countries, check yours