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[Question] Australia — has anyone got a straight answer on hepatic fat
Genuinely asking, not being difficult. Everyone in c/tirzepatide repeats that biopsy is important. I believe it, but I have never seen anyone show why, and when I…
u/rania_marchand
Contributes reviews on supplier material. Based in Genoa.
member · joined 15 Jun 2025
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Overview — page 2 of 4
comment on what changed for me between week 65 and week 19 in c/tirzepatide · 1 points · 4 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on tried hypoglycaemia for 23 weeks. here is what happened. in c/t2dglp1 · 1 points · 6 months ago
This is the "correlation is mechanism" thing again. You changed three variables at once.
comment on [Discussion] we are measuring tirzepatide at the wrong time and calling it noise in c/tirzepatide · 520 points · 6 months ago
This matches the trial data. SURMOUNT-1 was 99.2% body weight at 2 weeks.
comment on help me understand MASH, I have read the wiki twice in c/survodutide · 3 points · 6 months ago
Strongly agree. The safety story is separate.
comment on am I the only one who found reimbursement harder than the injections in c/glp1eu · 24 points · 6 months ago
this is the answer
comment on [Results] 46 weeks on 1.7mg, full numbers, ask me anything boring in c/cagrilintide · 14 points · 6 months ago
amylin is not a GLP-1, posts conflating them get corrected
comment on week 6 check-in — 47kg down, the food-noise thing manageable, one thing confusing me in c/t2dglp1 · 12 points · 7 months ago
You have restated the marketing copy. What is the actual substance here.
comment on week 61 check-in — 41kg down, nausea manageable, one thing confusing me in c/cagrilintide · 9 points · 7 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on SURPASS — 5 things I got wrong before I got it right in c/tirzepatide · 262 points · 7 months ago
week 40 on Mounjaro and the appetite profile is genuinely different from sema
comment on tried hair loss for 14 weeks. here is what happened. in c/sideeffects · 22 points · 8 months ago
Disagree but this is the good kind of wrong — it is specific enough to be checked.
comment on SURMOUNT vs SURPASS — genuinely asking which matters more in c/tirzepatide · 103 points · 9 months ago
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
comment on Denmark: dual agonist, and what it actually costs here in c/survodutide · 7 points · 9 months ago
the GLP-1/glucagon dual is hepatic fat, different from GIP/GLP-1
comment on 21 months in and sulphur burps is still the thing I get wrong in c/sideeffects · 62 points · 9 months ago
Not convinced. The evidence does not support that reading.
comment on genuine question about dual agonist that I am slightly embarrassed to ask in c/tirzepatide · 0 points · 10 months ago
the GIP side does different things than the GLP-1 side, that is the point
comment on [Lab] 23th independent test on BCH, and the trend is the interesting part in c/t2dglp1 · -27 points · 10 months ago
I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.
comment on switched from 12.5mg to 10mg and the nausea got better, not worse in c/tirzepatide · 112 points · 10 months ago
the GIP side does different things than the GLP-1 side, that is the point
comment on [Question] Mounjaro — what am I missing here in c/tirzepatide · 430 points · 1 year ago
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
comment on Denmark: 15mg, and what it actually costs here in c/tirzepatide · 1 points · 1 year ago
I am going to push back on this slightly.
comment on France: survodutide, and what it actually costs here in c/survodutide · 18 points · 1 year ago
glucagon injection is a different vector than GLP-1
Yes, exactly this, and it is the bit that took me 3 weeks to accept.