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GIP: what the trials say vs what this community says
Confession thread, sort of. I went from 10mg to 2.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 3 weeks…
u/santiago_villalobos
Contributes reviews on supplier material. Based in Catania.
member · joined 11 Feb 2025
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Overview — page 2 of 4
comment on tried HPLC for 6 weeks. here is what happened. in c/hplc · 13 points · 6 months ago
Injection volume and flow rate? Those affect resolution.
comment on am I the only one who found fertility harder than the injections in c/glp1women · 4 points · 6 months ago
Respectfully this is a sample of one presented as a finding.
comment on is it normal to get constipation at week 14 in c/orforglipron · 13 points · 7 months ago
Not to be pedantic but orforglipron and ATTAIN are being used interchangeably and they are not interchangeable in real life.
comment on SURPASS — 5 things I got wrong before I got it right in c/tirzepatide · 11 points · 7 months ago
do not crack the pen, we have been over this
comment on anyone else notice 15mg kicking in around week 24 in c/tirzepatide · 188 points · 8 months ago
Hard agree. The food noise disappears differently on the two compounds.
comment on small win: fertility stopped being a problem at week 55 in c/glp1women · -19 points · 8 months ago
the trials mostly studied men, perimenopause skipped
comment on is it normal to get nausea at week 10 in c/tirzepatide · 85 points · 9 months ago
do not crack the pen, we have been over this
comment on [Discussion] we are measuring MASH at the wrong time and calling it noise in c/survodutide · 4 points · 10 months ago
That is net peptide content, not purity. Different number, different meaning.
comment on genuine question about integration that I am slightly embarrassed to ask in c/hplc · 1 points · 11 months ago
the detector wavelength matters more than people think
comment on GIP: what the trials say vs what this community says in c/tirzepatide · 81 points · 11 months ago
the appetite change on tirz is more than just reduced hunger, it is different machinery
comment on GIP: what the trials say vs what this community says in c/tirzepatide · 189 points · 12 months ago
week 50 on Mounjaro and the appetite profile is genuinely different from sema
comment on unpopular opinion: orforglipron is massively overrated in c/orforglipron · 19 points · 1 year ago
Yeah, small molecule changes the whole game.
comment on tried method development for 12 weeks. here is what happened. in c/hplc · 8 points · 1 year ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on tried method development for 12 weeks. here is what happened. in c/hplc · 1 points · 1 year ago
area% and mass% are not the same and this whole post conflates them
comment on reading 15mg threads from 2024 and half of it aged badly in c/tirzepatide · 43 points · 1 year ago
the dual agonism hits different and that is why people describe it differently
comment on reading 15mg threads from 2024 and half of it aged badly in c/tirzepatide · 157 points · 1 year ago
The dual agonism story is real. The appetite is physically different from semaglutide alone.
comment on [Meta] proposal — a flair for survodutide posts in c/survodutide · 42 points · 1 year ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on [Meta] proposal — a flair for survodutide posts in c/survodutide · 171 points · 1 year ago
Which trial arm?
comment on Germany: SURMOUNT, and what it actually costs here in c/tirzepatide · 1 points · 1 year ago
The confident tone is doing a lot of work that the evidence is not.