Long-ish post, sorry. tl;dr at the bottom. I have been tracking tirzepatide against eGFR for 13 weeks because I could not find anyone who had. The correlation is weaker…
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Came for one answer, stayed for three years.
member · joined 15 Dec 2023
Overview — page 2 of 4
comment on what changed for me between week 70 and week 18 in c/newbiequestions · 25 points · 4 months ago
Yeah, that is totally normal for week 6.
comment on someone explain 15mg to me like I have not read a paper in years in c/tirzepatide · 145 points · 4 months ago
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
comment on small win: batch stopped being a problem at week 6 in c/coa · 2 points · 4 months ago
the method line is doing real work, not just window dressing
comment on what would you tell week-1 you about secretagogue in c/researchpeptides · 4 points · 5 months ago
research use only, handling and analysis, not administration
comment on what would you tell week-1 you about secretagogue in c/researchpeptides · 53 points · 5 months ago
Strongly agree. Evidence level matters.
comment on certificate of analysis — my 17-week log, condensed into one table in c/coa · 423 points · 5 months ago
What is the method line say? Not the technique, the actual method.
comment on certificate of analysis — my 17-week log, condensed into one table in c/coa · 1 points · 5 months ago
Respectfully this is a sample of one presented as a finding.
comment on certificate of analysis — my 17-week log, condensed into one table in c/coa · 234 points · 6 months ago
I am going to push back on this slightly.
Yes, exactly this, and it is the bit that took me 9 weeks to accept.
Right, the batch question again, but with numbers this time. I have 15 data points over 4 weeks. The pattern is consistent enough that I do not think it is chance, and…
comment on [Meta] proposal — a flair for SURMOUNT posts in c/tirzepatide · 8 points · 6 months ago
Cosigning.
Disagree on that part. 99.2% and 99.3% on the same vial is normal.
comment on the week one thing finally clicked for me and I want to write it down in c/newbiequestions · 129 points · 6 months ago
Not convinced. The evidence does not support that reading.
comment on what would you tell week-1 you about handling in c/researchpeptides · 17 points · 7 months ago
not approved for human use, full stop
comment on what would you tell week-1 you about handling in c/researchpeptides · 33 points · 7 months ago
regulatory status varies by country, check yours
comment on [Meta] the certificate of analysis rule is doing its job and people should stop complaining in c/coa · 306 points · 7 months ago
Mechanistically the bit that matters is water content. It explains most of the early profile and a decent chunk of the outcome.
comment on [Results] 96 weeks on 0.25mg, full numbers, ask me anything boring in c/newbiequestions · 17 points · 8 months ago
Week 14 checking in: nothing on the scale, no nausea, wondering if the pen is broken. No, it is just week 14.
comment on the normal thing finally clicked for me and I want to write it down in c/newbiequestions · 58 points · 9 months ago
link the wiki instead of retyping, but politely
Yes, exactly this, and it is the bit that took me 37 weeks to accept.
comment on 24 months in and TB-500 is still the thing I get wrong in c/researchpeptides · 74 points · 10 months ago
Mechanistically the bit that matters is thymosin. It explains most of the early profile and a decent chunk of the outcome.
comment on nobody warned me about sulphur burps and I would have liked the warning in c/tirzepatide · 628 points · 10 months ago
stalled on sema, tried tirz, and the curves were actually different shapes
comment on switched from 2.4mg to 1.7mg and the fatigue got better, not worse in c/newbiequestions · 168 points · 10 months ago
This is the "correlation is mechanism" thing again. You changed three variables at once.