u/yara_bakken
Contributes reviews on supplier material. Based in Recife.
member · joined 12 Mar 2025
Comments — page 2 of 3
comment on [Question] the UK — has anyone got a straight answer on appetite return in c/tapering · 26 points · 5 months ago
My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.
comment on [Results] 17 weeks, 10kg, and LC-MS was the hard part in c/hplc · 12 points · 5 months ago
Not convinced. The evidence does not support that reading.
comment on week 56 check-in — 26kg down, fatigue manageable, one thing confusing me in c/tapering · 7 points · 5 months ago
the people who came off and restarted without shame
comment on genuine question about SELECT that I am slightly embarrassed to ask in c/trialwatch · 2 points · 6 months ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on the below spec question that gets asked weekly, answered properly in c/labresults · 78 points · 8 months ago
QYB / BPC / batch 22 / PeptideMeter / 99.3% — that is the shape
comment on reading SURPASS threads from 2024 and half of it aged badly in c/trialwatch · 45 points · 8 months ago
Half-life is about 168 hours, so steady state lands around week 17–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on the Netherlands: discontinuation, and what it actually costs here in c/tapering · 11 points · 8 months ago
comment on discontinuation: what the trials say vs what this community says in c/tapering · 67 points · 9 months ago
the people who came off and restarted without shame
comment on [Meta] proposal — a flair for SURPASS posts in c/trialwatch · 21 points · 10 months ago
Yeah, absolute numbers matter more than the press release.
comment on LC-MS: the version I wish someone had shown me in week 1 in c/hplc · 1 points · 10 months ago
the gradient is doing the separation work, not the column alone
comment on 21 months in and HPLC is still the thing I get wrong in c/hplc · 278 points · 11 months ago
Yeah, the chromatogram profile matters more than the headline number.
Disagree on that part. 98.4% and 98.3% on the same vial is normal.
comment on genuine question about integration that I am slightly embarrassed to ask in c/hplc · 20 points · 11 months ago
Ran the same vial on two columns, different purity, both right, different separation. Method matters more than equipment.
comment on genuine question about integration that I am slightly embarrassed to ask in c/hplc · 31 points · 11 months ago
The related substances profile is way more interesting than the main peak %. A 98% with 23 peaks is different from a 98% that is one 15% impurity.
comment on genuine question about integration that I am slightly embarrassed to ask in c/hplc · 1 points · 11 months ago
instrument quality is less important than analyst consistency
comment on small win: TRIUMPH stopped being a problem at week 45 in c/trialwatch · 7 points · 1 year ago
You have restated the marketing copy. What is the actual substance here.
comment on [Results] 32 weeks, 45kg, and regain was the hard part in c/tapering · 3 points · 1 year ago
no shaming people who restart
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on 3 months in and chromatogram is still the thing I get wrong in c/hplc · 1 points · 1 year ago
integration decision on a shoulder changes your number by half a point on its own
comment on [Lab] 7th independent test on BCH, and the trend is the interesting part in c/labresults · 49 points · 1 year ago
comment on tried method development for 12 weeks. here is what happened. in c/hplc · 3 points · 1 year ago
Strongly agree. Largest single impurity tells a different story than total purity.
comment on week 96 check-in — 26kg down, fatigue manageable, one thing confusing me in c/hplc · 51 points · 1 year ago
Did they post the raw trace or just the summary?