ApoB is the most under-discussed thing in c/glp1science
Confession thread, sort of.
I went from 0.5mg to 12.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 11 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.
So now I have sulphur burps I did not need and a data point I cannot interpret. Two lessons in one.
Posting it in the hope that somebody at week 44 reads it before doing the same thing.
best — the order this archive was captured in
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
Small correction: the trial was 13 weeks, not 25. Does not change your point but people will quote it.
Slight fix: the number was 99.0, not 98.9. Decimal point, but a fairly consequential one.
Small correction: the trial was 23 weeks, not 7. Does not change your point but people will quote it.
This is correct. ApoB is the better marker.
baseline is the most important bloodwork measurement, you cannot collect it later
Same lab both times?
post reference ranges with your numbers, units differ by country and lab
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This is correct. ApoB is the better marker.
baseline is the most important ferritin measurement, you cannot collect it later
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
baseline is the most important eGFR measurement, you cannot collect it later
eGFR noise during rapid loss is expected
Sceptical. If this were true we would see it reflected in the data and we do not.
ApoB from 4 to 40 is movement, not noise
ApoB from 4 to 40 is movement, not noise
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
My ferritin went from 14 to 28 in 41 weeks. The A1c story shows up in the trend, not the single number.
- 1This is an urgent-care question wearing a forum question's clothes. Please…11 comments in this branch · started by u/lipid_panel_larry
- 2eGFR noise during rapid loss is expected5 comments in this branch · started by u/nnt_nate