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c/retatrutide·submitted 2 years ago by u/andres_sorensen

switched from 5mg to 2.5mg and the constipation got better, not worse

Trial Databranch of 11 comments

I have had 24 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 10 days on nominally the same lane, which matters more in summer than in February. The independent number came back 98.4% against a claimed…

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11 comments, started 2 years ago
u/employer_carveout276 points·2 years ago

the weight curves are unusually steep, which makes predicting individual response harder

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u/careful_gradient_again192 points·2 years ago

Did you actually measure heart rate or is that a feeling?

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u/employer_carveout46 points·2 years ago

phase 2 numbers are not maintenance numbers, cite the trial

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u/ledger_modmod · vetting313 points·2 years ago

the weight curves are unusually steep, which makes predicting individual response harder

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/farid_molnar77 points·2 years ago

retatrutide is not approved anywhere for human use, posts must not read as instructions

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u/nordic_pricing60 points·2 years ago

retatrutide is not approved anywhere for human use, posts must not read as instructions

Adding to this: TRIUMPH is doing more work than the comment implies.

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u/cold_chromatogram_only48 points·2 years ago·edited

research use only, handling and analysis, not protocols

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u/yannick_barros46 points·2 years ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/reta_and_regret240 points·2 years ago

the weight curves are unusually steep, which makes predicting individual response harder Counter-anecdote: opposite result, same dose.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/vito_beaulieu174 points·2 years ago

the glucagon component changes the side effect profile, not just the efficacy

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u/ismael_eriksen45 points·2 years ago

the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
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