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c/survodutide·submitted 11 months ago by u/thermal_mass_tom

anyone else notice dual agonist kicking in around week 80

Trial Databranch of 10 comments

Week 39 update. 10kg down from the start, early fullness basically gone since about week 91. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with early fullness. The part that surprised me is how much of this is…

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10 comments, started 11 months ago
u/border_paperwork112 points·11 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/liv_vukovic93 points·11 months ago

the GLP-1/glucagon dual is hepatic fat, different from GIP/GLP-1

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u/preservative_free_p35 points·11 months ago·edited

do not generalise from tirzepatide

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u/crosspost_bot_no20 points·11 months ago

not approved, descriptive posts only

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[deleted]8 points·11 months ago

[deleted]

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u/nadia_kjaer8 points·11 months ago

Yeah, glucagon co-agonism is genuinely different.

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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