genuine question about SURMOUNT that I am slightly embarrassed to ask
Confession thread, sort of. I went from 7.5mg to 2.4mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 6 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have…
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
Disagree but this is the good kind of wrong — it is specific enough to be checked.
press release SURMOUNT posts must be flaired until a publication exists
phase 2 is not phase 3, smaller n and shorter trial
SELECT reported a SELECT hazard ratio but the absolute event rate is what changes clinical practice.
phase 2 is not phase 3, smaller n and shorter trial
the discontinuation arms are the interesting part, not the FLOW endpoints
Not to be pedantic but TRIUMPH and STEP are being used interchangeably and they are not interchangeable in real life.
Disagree but this is the good kind of wrong — it is specific enough to be checked.