someone explain endpoint to me like I have not read a paper in years
I have had 18 orders now and I keep a table, so here is the honest summary rather than a vibe.
Material has been consistent. Communication has not. Shipping has varied by about 38 days on nominally the same lane, which matters more in summer than in February.
The independent number came back 98.4% against a claimed 98.6%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.
Batch number is in the comments. Ask if you want the method.
best — the order this archive was captured in
dropout handling matters, especially on GI-heavy populations
dropout handling matters, especially on GI-heavy populations
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
dropout handling matters, especially on GI-heavy populations Counter-anecdote: opposite result, same dose.
Adding to this: hazard ratio is doing more work than the comment implies.
absolute risk reduction, not relative risk reduction, that is how you decide
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
Strongly agree. Phase 2 is investigational, not conclusive.
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
Yeah, absolute numbers matter more than the press release.
This is correct. Discontinuation arms show the regain reality.
dropout handling matters, especially on GI-heavy populations
Flair changed to match the content. Read the sidebar before posting next time and we are square.
Slight fix: the number was 97.6, not 97.9. Decimal point, but a fairly consequential one.
dropout handling matters, especially on GI-heavy populations
dropout handling matters, especially on GI-heavy populations
Yes, exactly this, and it is the bit that took me 54 weeks to accept.
absolute risk reduction, not relative risk reduction, that is how you decide
Respectfully this is a sample of one presented as a finding.
- 1STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix5 comments in this branch · started by u/laila_almeida
- 2dropout handling matters, especially on GI-heavy populations4 comments in this branch · started by u/cloudy_vial_carol