u/britt_okwuosa

dose, date, weight, waist, reflux, labs

Not to be pedantic but packaging and excursion are being used interchangeably and they are not interchangeable in real life.

Adding to this: packaging is doing more work than the comment implies.

Tried both. Sema worked, tirz worked better for me, but my reflux profile was worse on tirz.

Small correction: the trial was 18 weeks, not 24. Does not change your point but people will quote it.

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

This is the "correlation is mechanism" thing again. You changed three variables at once.

a warm courier van is a bigger problem for a mixed vial than for dry powder

the 15mg is the top of the pen, not the required dose

This matches the trial data. SURMOUNT-1 was 97.9% body weight at 5 weeks.

Every time this gets posted it hits the front page and every time someone has to re-explain it.

Crossposting this to c/intlshipping because the people who need it are not reading this community.

Titration speed is a side-effect dial far more than an efficacy dial.

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

Slight fix: the number was 97.9, not 97.6. Decimal point, but a fairly consequential one.

Customs clearance took 16 days. Package sat unrefrigerated during that. Powder tested clean after, reconstituted solution probably would not have.

the GIP side does different things than the GLP-1 side, that is the point

Yes, exactly this, and it is the bit that took me 32 weeks to accept.

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

You have restated the marketing copy. What is the actual substance here.

Logger trace from my shipment: 3 hours at 21°C. Powder tested 94.2% against 96.8% claim. Tolerates more than the box implies.