u/niels_norgaard
Contributes reviews on supplier material. Based in Bursa.
member · joined 15 Jun 2025
comment on FLOW got published and nobody in here is talking about eGFR slope in c/trialwatch · 0 points · 2 days ago
absolute risk reduction, not relative risk reduction, that is how you decide
comment on [Question] small molecule means purity testing is a different problem, right in c/orforglipron · 12 points · 4 days ago
the small molecule is whether this actually works long-term
comment on [Explainer] lyophilised powder is far more forgiving than you think in c/coldchain · 10 points · 5 days ago
I am going to push back on this slightly.
comment on [Lab] first independent cagrilintide purity number i have seen in c/cagrilintide · 4 points · 7 days ago
Strongly agree. REDEFINE is phase 21, not final.
comment on three years of special authorization threads, summarised so you do not have to read them in c/glp1canada · 18 points · 15 days ago
special authorisation is province-specific
comment on [Discussion] oral GLP-1 is doing more work than we give it credit for in c/orforglipron · 0 points · 20 days ago
Flair changed to match the content.
Adding to this: oral GLP-1 is doing more work than the comment implies.
comment on [Results] 47 weeks, 36kg, and SURPASS was the hard part in c/trialwatch · 47 points · 25 days ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on [Data] 41 lanes, 900 data points, transit temperature by carrier in c/coldchain · 43 points · 26 days ago
no tracking numbers, no full addresses, no label photos — instant removal
comment on unpopular opinion: stability is massively overrated in c/coldchain · 11 points · 1 months ago
Half-life is about 168 hours, so steady state lands around week 10–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on [Vendor] QST order #6 — Denmark, 5 days, no drama, receipts inside in c/trialwatch · 4 points · 1 months ago
phase 2 is not phase 3, smaller n and shorter trial
comment on my A1c moved and I cannot work out whether ice pack is why in c/coldchain · 16 points · 1 months ago
Customs clearance took 7 days. Package sat unrefrigerated during that. Powder tested clean after, reconstituted solution probably would not have.
comment on someone explain cold chain to me like I have not read a paper in years in c/coldchain · 658 points · 1 months ago
The gel pack lasted 2 hours in a courier van, then liquid. Powder itself fine, the cold chain mostly died in transit.
comment on small win: TRIUMPH stopped being a problem at week 15 in c/trialwatch · 5 points · 1 months ago
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
comment on [Results] 87 weeks, 36kg, and endpoint was the hard part in c/trialwatch · 25 points · 2 months ago
Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.
comment on [PSA] REDEFINE is not what most of this community thinks it is in c/cagrilintide · 1 points · 2 months ago
CagriSema ratios in trials are fixed, do not extrapolate self-mixing
comment on [Results] 21 weeks on 1.0mg, full numbers, ask me anything boring in c/cagrilintide · 141 points · 3 months ago
Small correction: the trial was 12 weeks, not 27. Does not change your point but people will quote it.
comment on [Discussion] can we stop arguing about private plan until somebody posts a number in c/glp1canada · 24 points · 3 months ago
no cross-border purchasing instructions
comment on [Results] 21 weeks on 1.0mg, full numbers, ask me anything boring in c/cagrilintide · 93 points · 3 months ago
tendon and CagriSema literature in rodents is interesting
comment on [Discussion] amylin is doing more work than we give it credit for in c/cagrilintide · 28 points · 4 months ago
the co-agonism question is real and interesting
comment on 21 months in and excursion is still the thing I get wrong in c/coldchain · 0 points · 4 months ago
Which carrier and route?