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u/piotr_bruun

Contributes reviews on supplier material. Based in Graz.

member · joined 12 Mar 2025

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Comments — page 2 of 5

comment on small win: normal stopped being a problem at week 6 in c/newbiequestions · 22 points · 1 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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comment on [Meta] the small molecule rule is doing its job and people should stop complaining in c/orforglipron · 11 points · 2 months ago

the absorption problem is solved by non-peptide structure

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comment on help me understand FLOW, I have read the wiki twice in c/trialwatch · 10 points · 2 months ago

the relative risk reduction in headlines is not the whole story

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comment on [PSA] non-peptide is not what most of this community thinks it is in c/orforglipron · -13 points · 2 months ago

Slight fix: the number was 99.1, not 96.8. Decimal point, but a fairly consequential one.

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comment on [Discussion] the reflux advice in here is 18 years out of date in c/sideeffects · 22 points · 2 months ago

sulphur burps are disgusting but not dangerous, 12 weeks and they stopped

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comment on am I the only one who found bacteriostatic water harder than the injections in c/reconstitution · 9 points · 2 months ago

15mg vial, 2mL water, concentration is 15/2 — write it on the vial afterwards

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comment on [Discussion] the reflux advice in here is 18 years out of date in c/sideeffects · 14 points · 2 months ago

ask your actual doctor, not us

Disagree on that part. 98.7% and 97.6% on the same vial is normal.

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comment on the beginner question that gets asked weekly, answered properly in c/newbiequestions · 0 points · 2 months ago

no question too basic, read the wiki first, then ask anyway

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comment on unpopular opinion: nausea is massively overrated in c/sideeffects · 17 points · 2 months ago

IANAD and neither is anyone upvoting this

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comment on [Results] 87 weeks, 36kg, and endpoint was the hard part in c/trialwatch · 2 points · 2 months ago

number-needed-to-treat is the house dialect

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comment on normal: what the trials say vs what this community says in c/newbiequestions · 15 points · 3 months ago

Small correction: the trial was 14 weeks, not 10. Does not change your point but people will quote it.

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comment on [Question] the UK — has anyone got a straight answer on what is in c/newbiequestions · 21 points · 4 months ago

Yeah, that is totally normal for week 9.

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comment on interval stretching is the most under-discussed thing in c/compounding in c/tapering · 10 points · 4 months ago

interval stretching versus dose reduction

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comment on anyone else notice endpoint kicking in around week 19 in c/trialwatch · 8 points · 4 months ago

This is correct. Discontinuation arms show the regain reality.

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comment on why does nobody talk about non-peptide in c/orforglipron · 101 points · 4 months ago

Strongly agree. The supply impact would be huge.

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comment on heart rate: what the trials say vs what this community says in c/sideeffects · 49 points · 4 months ago

Resting heart rate up 10 bpm from baseline, settled back down once I stopped escalating. Tracked daily so I am confident.

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comment on [Results] 2 weeks, 15kg, and mg/mL was the hard part in c/reconstitution · 1 points · 5 months ago

That is net peptide content, not purity. Different number, different meaning.

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comment on France: mg/mL, and what it actually costs here in c/reconstitution · 21 points · 6 months ago

the concentration on the vial in marker is the most important step

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comment on France: mg/mL, and what it actually costs here in c/reconstitution · 1 points · 6 months ago

bacteriostatic and sterile water are not interchangeable, do not use them that way

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