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c/survodutide·submitted 2 months ago by u/tomas_lokken

glucagon — 17 things I got wrong before I got it right

Cautionbranch of 8 comments

Quick one. Canada here. MASH works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 13 weeks and cost roughly what I expected. The admin was worse than the cost.…

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8 comments, started 2 months ago
u/renal_outcomes_rnephro-curious117 points·2 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/liver_enzyme_lizMOD58 points·2 months ago

Retitled to remove editorialising. Put the evidence in the body.

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u/jarno_adeyemi54 points·2 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

Adding to this: biopsy is doing more work than the comment implies.

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u/milan_mensah16 points·2 months ago·edited

not approved, descriptive posts only

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u/kian_ferreira146 points·2 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/laila_yilmaz61 points·2 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/hana_lehtinen205 points·2 months ago

the safety profile is not just tirzepatide amplified

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[removed]150 points·2 months ago

[removed by moderator]

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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