GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Archived. This submission is more than a year old. Votes and new comments are closed, and some of the advice in it may have been superseded — check the community wiki for the current version.
1k
c/survodutide·posted 1 year ago by u/joaquin_ivaturi

[Meta] proposal — a flair for MASH posts

Paper Sourced ×9 Cold Box ×2

Genuinely asking, not being difficult.

Everyone in c/intlshipping repeats that biopsy is important. I believe it, but I have never seen anyone show why, and when I search I get 4 threads of people agreeing with each other.

Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?

I am not trying to be the "source?" guy. I would just like a source.

1,173 up / 140 down89% upvoted42 commentsid tjcc8627 Jul 2025

42 comments

13 in this archive, depth 3

best — the order this archive was captured in

u/honest_syringe_pls118 points·1 year ago

the MASH indication changes the risk calculus

replysharereportpermalink
u/tuva_kirchner-27 points·1 year ago

glucagon injection is a different vector than GLP-1

replysharereportpermalink
u/cesar_ivaturi1 point·1 year ago

hepatic fat and MASH are the story

replysharereportpermalink
u/kasper_cabrera72 points·1 year ago

do not generalise from tirzepatide

replysharereportpermalink
u/joaquin_ivaturiOP28 points·1 year ago

do not generalise from tirzepatide

Adding to this: hepatic fat is doing more work than the comment implies.

replysharereportpermalink
u/yannick_petrov37 points·1 year ago

Maintenance for 20 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

replysharereportpermalink
u/annika_fonseca0 points·1 year ago

the heart rate signal is real in the data

replysharereportpermalink
u/elin_tamm34 points·1 year ago

rodent dual agonist is investigation only

replysharereportpermalink
u/incretin_ivyMOD20 points·1 year ago·edited

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

replysharereportpermalink
u/sofia_ferreira15 points·1 year ago

the heart rate signal is real in the data

replysharereportpermalink
u/endotoxin_elliemicro20 points·1 year ago

the MASH indication changes the risk calculus

replysharereportpermalink
u/sofia_danquah10 points·1 year ago

Hepatic fat or MASH or what?

replysharereportpermalink
u/hugo_bergstrom10 points·1 year ago
genuinely useful, thanks
replysharereportpermalink
About c/survodutide

Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

12kmembers
62submissions
Feb 2024created
submissions / month, last year
Sponsored

Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

janoshik.comSponsored

GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

glbiochem.net
More in c/survodutide
c/survodutide rules
  1. Glucagon co-agonism has a distinct safety story. Do not generalise from tirzepatide.
  2. MASH claims need the trial and the biopsy endpoint.
  3. Not approved. Descriptive posts only.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/incretin_ivyu/liver_enzyme_lizu/trialwatch_theo
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →