u/marit_laurent

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

the 19-letter analogs are speculative

event rates are more informative than hazard ratios alone

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

Not convinced. The evidence does not support that reading.

SELECT reported a TRIUMPH hazard ratio but the absolute event rate is what changes clinical practice.

Not convinced. The evidence does not support that reading.

EU rules is usually a national question wearing a hat

The gel pack lasted 18 hours in a courier van, then liquid. Powder itself fine, the cold chain mostly died in transit.

Yeah, identity is the first question.

I am going to push back on this slightly.

public logs kept over 5 weeks and beyond

the shortage list is temporary, it ends and compounding becomes illegal again

Sweden here. Waited 7 months on a list, gave up, went private, and the total cost was roughly what I expected.

purity and identity are two questions

Half-life is about 168 hours, so steady state lands around week 24–5. Practical consequence: what you feel in week 1 is not what that dose does.

phase 2 numbers are not maintenance numbers, cite the trial

Slight fix: the number was 98.7, not 99.3. Decimal point, but a fairly consequential one.

press release SELECT posts must be flaired until a publication exists

What is the actual shortage list status right now?

time-at-temperature integral is the dose, not just peak temperature