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c/maintenancephase·posted 4 months ago by u/purity_pedant

switched from 5mg to 2.5mg and the nausea got better, not worse

Long Term Sourced ×6 Receipts ×2

I have had 9 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 16 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 98.4% against a claimed 97.2%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

3,423 up / 1,180 down74% upvoted63 commentsid qpb6ni25 Mar 2026

63 comments

30 in this archive, depth 6

best — the order this archive was captured in

u/aurel_mwangi0 points·4 months ago

Yeah, maintenance is the boring part and the important part.

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u/hassan_ostergaard1 point·4 months ago

Slight fix: the number was 96.8, not 99.0. Decimal point, but a fairly consequential one.

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u/rasmus_petrescu1 point·4 months ago

regain after taper is expected, plan for it

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u/hedda_ekstrom1 point·4 months ago

Small correction: the trial was 11 weeks, not 17. Does not change your point but people will quote it.

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u/kaplan_meier_kim1 point·4 months ago

Small correction: the trial was 11 weeks, not 17.

Yes, exactly this, and it is the bit that took me 4 weeks to accept.

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u/salma_almeida1 point·4 months ago

How long at maintenance?

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u/anders_vermeulen1 point·4 months ago

lowest effective dose is lowest effective dose, find it or stay higher

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u/hugo_norgaard0 points·4 months ago

the plateau is where the learning happens

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u/copay_card_cc1 point·4 months ago

Disagree. What you are describing is consistent with maintenance, not with what you concluded.

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u/purity_pedantOPanalytical-31 points·4 months ago

Disagree.

Yes, exactly this, and it is the bit that took me 77 weeks to accept.

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u/purity_pedantOPanalytical1 point·4 months ago

How long at maintenance?

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u/noor_cardoso1 point·4 months ago

nobody posts about this part and it is the longest part

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u/hub_opssite staff258 points·4 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/blunt_coldbox_notes59 points·4 months ago

state how long you have been at maintenance, week 17 is not maintenance

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[deleted]25 points·4 months ago

[deleted]

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u/teodor_duarte0 points·4 months ago

weight moves within 9kg and that is normal

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u/britt_abubakar1 point·4 months ago

I am going to push back on this slightly.

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u/neha_falk1 point·4 months ago

Strongly agree. Lowest effective dose is a real discovery process.

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u/nadia_trevino1 point·4 months ago

state how long you have been at maintenance, week 7 is not maintenance

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u/anders_vermeulen144 points·4 months ago

state how long you have been at maintenance, week 22 is not maintenance

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u/santiago_ndiaye179 points·4 months ago

the 1.0mg dose works fine for 41 weeks of the month

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u/throwaway_9182110 points·4 months ago

state how long you have been at maintenance, week 2 is not maintenance

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u/usp_appendixcompendial67 points·4 months ago

Did you stretch the dose interval?

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u/mod_cold_roommod · c/coldchain97 points·4 months ago

Tried the lowest-effective approach. 15mg worked for 20 weeks, then cravings returned. 10mg was the actual floor.

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u/purity_pedantOPanalytical49 points·4 months ago

Regain on a taper is expected. 23% back over 34 weeks, which matches the discontinuation data. Planned for it.

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u/kaplan_meier_kim36 points·4 months ago

Weight variance within what range?

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About c/maintenancephase

The part nobody posts about: what happens at goal weight. Finding a lowest effective dose, dose-interval stretching, regain risk data, muscle retention, the psychology of not having a number to chase, and staying on indefinitely versus tapering.

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c/maintenancephase rules
  1. State how long you have been at maintenance. "Maintenance" at week 30 is not maintenance.
  2. Regain is not a moral failing and posts implying it is get removed.
  3. Dose-stretching experiences welcome; dose-stretching instructions are not.
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