u/forest_plot_fiona
Confidence intervals are the entire story. The point estimate is the headline.
long-standing contributor · stats · joined 19 Nov 2023
Overview — page 5 of 5
comment on stalled for 18 weeks at 1.0mg and I refuse to panic this time in c/cagrilintide · 247 points · 1 year ago
research use only, no human protocols in posts
comment on Germany: contraception, and what it actually costs here in c/glp1women · 670 points · 1 year ago
Half-life is about 168 hours, so steady state lands around week 11–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on [Discussion] fertility is doing more work than we give it credit for in c/glp1women · 24 points · 1 year ago
Strongly agree. Cycle changes are documented.
comment on tried CagriSema for 12 weeks. here is what happened. in c/cagrilintide · 16 points · 1 year ago
Strongly agree. REDEFINE is phase 14, not final.
comment on the FLOW question that gets asked weekly, answered properly in c/trialwatch · 6 points · 1 year ago
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
comment on [Question] how do you actually verify REDEFINE in c/cagrilintide · 76 points · 1 year ago
long-acting amylin is co-agonism, different satiety profile
Yes, exactly this, and it is the bit that took me 50 weeks to accept.
comment on someone explain tirzepatide to me like I have not read a paper in years in c/tirzepatide · 1 points · 1 year ago
Hard agree. The food noise disappears differently on the two compounds.
comment on someone explain tirzepatide to me like I have not read a paper in years in c/tirzepatide · 16 points · 1 year ago
Half-life is about 168 hours, so steady state lands around week 17–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on someone explain tirzepatide to me like I have not read a paper in years in c/tirzepatide · 7 points · 1 year ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on three years of SURMOUNT threads, summarised so you do not have to read them in c/trialwatch · 1 points · 1 year ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on [Results] 77 weeks, 21kg, and endpoint was the hard part in c/trialwatch · 6 points · 2 years ago
press release TRIUMPH posts must be flaired until a publication exists
comment on does SURPASS actually matter or is it forum lore at this point in c/trialwatch · 237 points · 2 years ago
Flair changed to match the content. Read the sidebar before posting next time and we are square.
comment on [Results] 41 weeks on 7.5mg, full numbers, ask me anything boring in c/tirzepatide · 257 points · 2 years ago
Week 26 on Mounjaro and 34kg down. The appetite reduction feels different from sema in ways I do not have words for yet.
comment on 9 months in and SURMOUNT is still the thing I get wrong in c/trialwatch · 56 points · 2 years ago
the 19 week readout is different from the 8 week readout
comment on [Vendor] QST order #19 — Canada, 15 days, no drama, receipts inside in c/bloodwork · 52 points · 2 years ago
Yeah, baseline matters more than any later number.
comment on [Discussion] we are measuring Zepbound at the wrong time and calling it noise in c/tirzepatide · 15 points · 2 years ago
SURMOUNT data is messier than STEP data but the weight loss is there
comment on am I the only one who found SURMOUNT harder than the injections in c/trialwatch · 1 points · 2 years ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on tried tirzepatide for 15 weeks. here is what happened. in c/tirzepatide · 9 points · 2 years ago
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.