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u/sofia_wikstrom

Contributes reviews on supplier material. Based in Leuven.

member · joined 15 Jun 2025

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Comments — page 4 of 5

comment on [Discussion] we are measuring Wegovy at the wrong time and calling it noise in c/semaglutide · 85 points · 12 months ago

my TSH moved before the scale did and i nearly missed it

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on genuine question about titration that I am slightly embarrassed to ask in c/semaglutide · 474 points · 1 year ago

pens are overpriced, research vials are research grade, same molecule different price

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comment on switched from 1.0mg to 2.5mg and the sulphur burps got better, not worse in c/sideeffects · 34 points · 1 year ago

Are you on a pen or research vial?

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on switched from 1.0mg to 2.5mg and the sulphur burps got better, not worse in c/sideeffects · 18 points · 1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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comment on phase 2 — my 12-week log, condensed into one table in c/retatrutide · 6 points · 1 year ago

nobody should be giving this to anyone without extensive monitoring

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comment on [Results] 16 weeks on 15mg, full numbers, ask me anything boring in c/semaglutide · 1 points · 1 year ago

the 2.4mg dose is not the target, it is just what the pen goes up to

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comment on SELECT — 9 things I got wrong before I got it right in c/trialwatch · 75 points · 1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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comment on genuine question about dose escalation that I am slightly embarrassed to ask in c/retatrutide · -36 points · 1 year ago

heart rate and dose escalation need actual measurements, not impressions

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comment on regain vs dose stretching — genuinely asking which matters more in c/maintenancephase · 13 points · 1 year ago

the lowest dose you can stay on is not the lowest dose that works

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comment on [Lab] 4th independent test on BCH, and the trend is the interesting part in c/trialwatch · 45 points · 1 year ago

SELECT reported a SURMOUNT hazard ratio but the absolute event rate is what changes clinical practice.

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comment on [Lab] 4th independent test on BCH, and the trend is the interesting part in c/trialwatch · 43 points · 1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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comment on [Lab] 4th independent test on BCH, and the trend is the interesting part in c/trialwatch · 3 points · 1 year ago

STEP 1 readout: 94.2% mean weight loss, absolute numbers matter. Spread around that mean is enormous.

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comment on what would you tell week-1 you about dose escalation in c/retatrutide · 179 points · 1 year ago

Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.

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comment on [Question] how do you actually verify food noise in c/semaglutide · 352 points · 1 year ago

okay but what dose of sema are you on

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comment on [Results] 37 weeks, 16kg, and phase 2 was the hard part in c/retatrutide · 72 points · 1 year ago

the glucagon component changes the side effect profile, not just the efficacy

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comment on nausea — my 9-week log, condensed into one table in c/sideeffects · 139 points · 1 year ago

You have restated the marketing copy. What is the actual substance here.

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comment on dose escalation: what the trials say vs what this community says in c/retatrutide · 10 points · 1 year ago

That is net peptide content, not purity. Different number, different meaning.

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comment on regain — my 14-week log, condensed into one table in c/maintenancephase · -29 points · 1 year ago

the 1.7mg dose works fine for 36 weeks of the month

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comment on what changed for me between week 40 and week 83 in c/sideeffects · 187 points · 1 year ago

hair loss is real and usually reversible when you stabilize

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