u/hub_ops
Site operations. I keep the lights on and the sitemap honest. Not a clinician, not a vendor.
admin · site staff · joined 2 Aug 2023
Overview — page 2 of 5
comment on [Long Term] what my labs look like three years in in c/maintenancephase · 23 points · 27 days ago
What dose are you on?
comment on [Vendor] QST order #9 — Spain, 31 days, no drama, receipts inside in c/tirzepatide · 486 points · 1 months ago
Did the sulphur burps feel the same as on tirz or genuinely different?
comment on bacteriostatic water is the most under-discussed thing in c/cagrilintide in c/reconstitution · 58 points · 1 months ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on [Results] 26 weeks on 5mg, full numbers, ask me anything boring in c/reconstitution · 15 points · 1 months ago
swirl, do not shake, or you are courting oxidation
comment on week 71 check-in — 6kg down, constipation manageable, one thing confusing me in c/reconstitution · 55 points · 1 months ago
This is correct. 2mL versus 2mL is the common mistake.
comment on [Discussion] the archive-after-a-year policy: keep, change, or scrap in c/meta · 10 points · 1 months ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on [PSA] satiety is not what most of this community thinks it is in c/cagrilintide · 109 points · 1 months ago
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
comment on small win: TRIUMPH stopped being a problem at week 15 in c/trialwatch · 4 points · 1 months ago
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
Adding to this: SURMOUNT is doing more work than the comment implies.
comment on switched from 0.25mg to 1.7mg and the constipation got better, not worse in c/maintenancephase · 40 points · 2 months ago
Strongly agree. Lowest effective dose is a real discovery process.
comment on unpopular opinion: mg/mL is massively overrated in c/reconstitution · 161 points · 2 months ago
never post a calculation as advice without stating the concentration
comment on SELECT: the version I wish someone had shown me in week 1 in c/trialwatch · 17 points · 2 months ago
off-label use data is different from approved-indication data
Disagree on that part. 98.7% and 98.9% on the same vial is normal.
comment on 18 months in and TRIUMPH is still the thing I get wrong in c/trialwatch · 4 points · 2 months ago
Yeah, absolute numbers matter more than the press release.
comment on unpopular opinion: reconstitution is massively overrated in c/reconstitution · 7 points · 2 months ago
dosing errors come from people reconstituting two vials differently and forgetting which is which
comment on what changed for me between week 15 and week 58 in c/tirzepatide · 9 points · 3 months ago
SURMOUNT data is messier than STEP data but the weight loss is there
comment on [Discussion] we are measuring moderation at the wrong time and calling it noise in c/meta · 1 points · 3 months ago
Respectfully this is a sample of one presented as a finding.
comment on [Results] 22 weeks, 45kg, and maintenance was the hard part in c/maintenancephase · 18 points · 3 months ago
weight moves within 2kg and that is normal Disagree on that part.
Yes, exactly this, and it is the bit that took me 75 weeks to accept.
comment on [Meta] the dual agonist rule is doing its job and people should stop complaining in c/survodutide · 0 points · 3 months ago
Small correction: the trial was 5 weeks, not 37. Does not change your point but people will quote it.
comment on Canada: endpoint, and what it actually costs here in c/trialwatch · 3 points · 3 months ago
number-needed-to-treat is the house dialect
Disagree on that part. 93.7% and 99.3% on the same vial is normal.
comment on three years of dose stretching threads, summarised so you do not have to read them in c/maintenancephase · 365 points · 3 months ago
Every time this gets posted it hits the front page and every time someone has to re-explain it.
comment on switched from 5mg to 2.5mg and the nausea got better, not worse in c/maintenancephase · 258 points · 4 months ago
The confident tone is doing a lot of work that the evidence is not.