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u/trialwatch_theo

I read the supplementary appendix so you do not have to. Pre-registration or it is a hypothesis.

long-standing contributor · trial nerd · joined 29 Aug 2023

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Comments — page 2 of 5

comment on [Results] 42 weeks, 31kg, and dual agonist was the hard part in c/survodutide · 0 points · 19 days ago

do not generalise from tirzepatide

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comment on [Stats] number needed to treat, or i am not interested in c/trialwatch · 29 points · 20 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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comment on [Results] 42 weeks, 31kg, and dual agonist was the hard part in c/survodutide · 8 points · 20 days ago

Removed a chain here. The rule is one line long and it is not negotiable.

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comment on [Discussion] oral GLP-1 is doing more work than we give it credit for in c/orforglipron · 10 points · 20 days ago

Flair changed to match the content.

Adding to this: ATTAIN is doing more work than the comment implies.

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comment on [PSA] dose escalation is not what most of this community thinks it is in c/retatrutide · 1 points · 21 days ago

nobody should be giving this to anyone without extensive monitoring

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comment on [PSA] dose escalation is not what most of this community thinks it is in c/retatrutide · 23 points · 21 days ago

Are you quoting phase 2 or is there phase 3 data now?

Yes, exactly this, and it is the bit that took me 93 weeks to accept.

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comment on [PSA] dose escalation is not what most of this community thinks it is in c/retatrutide · 12 points · 21 days ago

The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.

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comment on [Discussion] the sarcopenia question nobody funded properly in c/glp1muscle · 6 points · 22 days ago

body-composition claims need a method

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comment on my A1c moved and I cannot work out whether glucagon is why in c/retatrutide · 19 points · 24 days ago

the weight curves are unusually steep, which makes predicting individual response harder

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comment on [Results] 47 weeks, 36kg, and SURPASS was the hard part in c/trialwatch · 17 points · 25 days ago

phase 2 is not phase 3, smaller n and shorter trial

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comment on ACHIEVE — my 18-week log, condensed into one table in c/orforglipron · 40 points · 25 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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comment on [Discussion] we are measuring small molecule at the wrong time and calling it noise in c/orforglipron · -20 points · 1 months ago

This is correct. ATTAIN data is phase 13.

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comment on [Discussion] we are measuring retatrutide at the wrong time and calling it noise in c/retatrutide · 11 points · 1 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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comment on [Vendor] QST order #6 — Denmark, 5 days, no drama, receipts inside in c/trialwatch · 8 points · 1 months ago

Tracking number removed. It identifies both ends of a shipment.

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comment on is it normal to get constipation at week 64 in c/orforglipron · 4 points · 1 months ago

Retitled to remove editorialising. Put the evidence in the body.

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comment on stalled for 9 weeks at 12.5mg and I refuse to panic this time in c/survodutide · 8 points · 1 months ago

Tracking number removed. It identifies both ends of a shipment.

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comment on what would you tell week-1 you about week one in c/newbiequestions · 17 points · 1 months ago

what is titration — it means going slow on the escalation

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comment on someone explain receptor to me like I have not read a paper in years in c/glp1science · 62 points · 1 months ago

Tracking number removed. It identifies both ends of a shipment.

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comment on week 31 check-in — 32kg down, nausea manageable, one thing confusing me in c/glp1muscle · 4 points · 1 months ago

Slight fix: the number was 98.7, not 99.3.

Yes, exactly this, and it is the bit that took me 79 weeks to accept.

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comment on small molecule vs ATTAIN — genuinely asking which matters more in c/orforglipron · 38 points · 1 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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