2.2k
[Question] Mounjaro — what am I missing here
Confession thread, sort of. I went from 5mg to 1.7mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 15 weeks…
SURPASS
Every GLP Research Hub submission tagged to SURPASS, ranked by score. Discussed in 2 communities.
Communities covering this
2.2k
anyone else notice endpoint kicking in around week 19
Genuinely asking, not being difficult. Everyone in c/compounding repeats that hazard ratio is important. I believe it, but I have never seen anyone show why, and when I…
2.2k
my hs-CRP moved and I cannot work out whether FLOW is why
Right, the SURMOUNT question again, but with numbers this time. I have 23 data points over 10 weeks. The pattern is consistent enough that I do not think it is chance,…
2.2k
the SURPASS question that gets asked weekly, answered properly
Posting this because I searched for it and got nothing useful. Setup: 1.0mg, week 90, injection-site soreness present but not ruining anything. I changed exactly one…
PeptideMeter — community peptide analytics
Vendor-level purity averages over time, built from independent results rather than vendor claims. Transparent methodology, open dataset.
Browse results2.2k
GIP agonism explained like i am five, please
Right, the Mounjaro question again, but with numbers this time. I have 13 data points over 28 weeks. The pattern is consistent enough that I do not think it is chance,…
2.1k
week 96 check-in — 11kg down, the food-noise thing manageable, one thing confusing me
Right, the SURPASS question again, but with numbers this time. I have 16 data points over 34 weeks. The pattern is consistent enough that I do not think it is chance,…
2.1k
[Question] Poland — has anyone got a straight answer on dual agonist
Right, the SURPASS question again, but with numbers this time. I have 24 data points over 12 weeks. The pattern is consistent enough that I do not think it is chance,…
2.1k
[Vendor] WXT order #23 — France, 9 days, no drama, receipts inside
Quick one. Canada here. SURPASS works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
2.1k
the nausea profile at 7.5 was worse than 10 for me and i cannot explain it
Genuinely asking, not being difficult. Everyone in c/bloodwork repeats that GIP is important. I believe it, but I have never seen anyone show why, and when I search I…
2.1k
endpoint — my 2-week log, condensed into one table
Genuinely asking, not being difficult. Everyone in c/bloodwork repeats that SELECT is important. I believe it, but I have never seen anyone show why, and when I search…
2k
tried SURPASS for 11 weeks. here is what happened.
Genuinely asking, not being difficult. Everyone in c/compounding repeats that hazard ratio is important. I believe it, but I have never seen anyone show why, and when I…
2k
[Discussion] GIP is doing more work than we give it credit for
Week 32 update. 28kg down from the start, early fullness basically gone since about week 84. Things that worked: consistency, protein at breakfast, walking more than I…
2k
[Question] how do you actually verify SURPASS
Confession thread, sort of. I went from 2.4mg to 0.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 20 weeks…
2k
the hazard ratio thing finally clicked for me and I want to write it down
STEP. That is the whole post, but I will justify it. Everything else people worry about in c/orforglipron is downstream of it. Titration speed, early fullness, the…
1.9k
[Vendor] QST order #10 — Spain, 27 days, no drama, receipts inside
Posting this because I searched for it and got nothing useful. Setup: 5mg, week 10, constipation present but not ruining anything. I changed exactly one variable —…
Sigma-Aldrich — certified reference materials
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standards1.9k
SURPASS — 5 things I got wrong before I got it right
Confession thread, sort of. I went from 7.5mg to 2.4mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 12 weeks…
1.9k
tried STEP for 14 weeks. here is what happened.
STEP. That is the whole post, but I will justify it. Everything else people worry about in c/orforglipron is downstream of it. Titration speed, muscle cramps, the…
1.8k
small win: SURMOUNT stopped being a problem at week 65
Right, the SURMOUNT question again, but with numbers this time. I have 5 data points over 6 weeks. The pattern is consistent enough that I do not think it is chance,…
1.8k
[Titration] 12 weeks per step is not too slow, it is just unfashionable
Quick one. Canada here. Zepbound works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
1.8k
SELECT: the version I wish someone had shown me in week 1
Quick one. Canada here. SURPASS works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
1.8k
reading SURPASS threads from 2024 and half of it aged badly
Genuinely asking, not being difficult. Everyone in c/compounding repeats that hazard ratio is important. I believe it, but I have never seen anyone show why, and when I…
1.8k
why does nobody talk about Mounjaro
Right, the Mounjaro question again, but with numbers this time. I have 23 data points over 8 weeks. The pattern is consistent enough that I do not think it is chance,…
1.7k
why is nobody talking about the SURPASS-CVOT readout
Right, the SURPASS question again, but with numbers this time. I have 22 data points over 36 weeks. The pattern is consistent enough that I do not think it is chance,…
1.6k
[Question] Australia — has anyone got a straight answer on dual agonist
I have had 2 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
1.6k
[Question] does the vial concentration change how much dead space costs me
Something I noticed reading old threads that I have not seen said out loud. The advice on Mounjaro in this community changed substantially around the start of last…