2.9k
help me understand glucagon, I have read the wiki twice
Been lurking in c/sideeffects for about 5 months and finally have something worth posting. Short version: week 24, 1.7mg, and triple agonist is the bit I still cannot…
glucagon
Every GLP Research Hub submission tagged to glucagon, ranked by score. Discussed in 2 communities.
Communities covering this
2.8k
switched from 0.5mg to 0.25mg and the muscle cramps got better, not worse
Posting this because I searched for it and got nothing useful. Setup: 1.7mg, week 53, injection-site soreness present but not ruining anything. I changed exactly one…
2.8k
the triple agonist thing finally clicked for me and I want to write it down
Something I noticed reading old threads that I have not seen said out loud. The advice on TRIUMPH in this community changed substantially around the start of last year,…
2.8k
am I the only one who found TRIUMPH harder than the injections
phase 2. That is the whole post, but I will justify it. Everything else people worry about in c/glp1canada is downstream of it. Titration speed, early fullness, the…
Sigma-Aldrich — certified reference materials
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standards2.7k
[Question] how do you actually verify dose escalation
Quick one. Canada here. glucagon works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
2.7k
[Lab] split one vial across Medutest and Janoshik — 96.2% and 99.2%
I have had 19 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
2.7k
biopsy: the version I wish someone had shown me in week 1
Posting this because I searched for it and got nothing useful. Setup: 1.0mg, week 77, constipation present but not ruining anything. I changed exactly one variable —…
2.6k
phase 2 — my 13-week log, condensed into one table
Posting this because I searched for it and got nothing useful. Setup: 0.5mg, week 46, constipation present but not ruining anything. I changed exactly one variable —…
2.6k
anyone else notice dual agonist kicking in around week 80
Week 39 update. 10kg down from the start, early fullness basically gone since about week 91. Things that worked: consistency, protein at breakfast, walking more than I…
2.6k
14 months in and dose escalation is still the thing I get wrong
I have had 12 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
2.5k
genuine question about glucagon that I am slightly embarrassed to ask
Week 17 update. 13kg down from the start, muscle cramps basically gone since about week 69. Things that worked: consistency, protein at breakfast, walking more than I…
2.5k
anyone else notice retatrutide kicking in around week 49
Confession thread, sort of. I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 3 weeks…
2.4k
[Meta] proposal — a flair for survodutide posts
Long-ish post, sorry. tl;dr at the bottom. I have been tracking survodutide against eGFR for 21 weeks because I could not find anyone who had. The correlation is weaker…
2.3k
TRIUMPH: what the trials say vs what this community says
Right, the triple agonist question again, but with numbers this time. I have 10 data points over 30 weeks. The pattern is consistent enough that I do not think it is…
2.3k
[Question] dose escalation — what am I missing here
Something I noticed reading old threads that I have not seen said out loud. The advice on TRIUMPH in this community changed substantially around the start of last year,…
Janoshik Analytical — independent HPLC & mass spec
Send the vial, get the number. Third-party purity and identity testing, results published to you regardless of what they say.
Test a vialSponsoredGL Biochem (Shanghai) Ltd. — the synthesis house
Est. 1998. ISO 9001 and cGMP, 1,500+ staff, 200+ patents. There is a fair chance the vial you are about to send for testing started here. Batch-specific COA as standard.
glbiochem.net2.3k
my A1c moved and I cannot work out whether phase 2 is why
Long-ish post, sorry. tl;dr at the bottom. I have been tracking retatrutide against eGFR for 31 weeks because I could not find anyone who had. The correlation is weaker…
2.3k
week 51 check-in — 12kg down, injection-site soreness manageable, one thing confusing me
Been lurking in c/progresspics for about 24 months and finally have something worth posting. Short version: week 56, 1.7mg, and TRIUMPH is the bit I still cannot get a…
2.2k
reading MASH threads from 2024 and half of it aged badly
Long-ish post, sorry. tl;dr at the bottom. I have been tracking survodutide against triglycerides for 31 weeks because I could not find anyone who had. The correlation…
2.1k
retatrutide vs triple agonist — genuinely asking which matters more
Posting this because I searched for it and got nothing useful. Setup: 1.7mg, week 30, sulphur burps present but not ruining anything. I changed exactly one variable —…
2k
week 11 check-in — 31kg down, muscle cramps manageable, one thing confusing me
Genuinely asking, not being difficult. Everyone in c/newbiequestions repeats that dose escalation is important. I believe it, but I have never seen anyone show why, and…
1.9k
[Vendor] QST order #8 — Canada, 9 days, no drama, receipts inside
Confession thread, sort of. I went from 0.5mg to 12.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 24 weeks…
1.9k
reta phase 2 was −24.2% at 48 weeks and people quote it like it is a maintenance number
Jastreboff et al., N Engl J Med , 2023. Phase 2. Forty-eight weeks. Mean change −24.2% in the highest dose arm. Every one of those qualifiers gets dropped when the…
1.9k
[Lab] two reta batches, two services, 98.4% and 97.9%
Genuinely asking, not being difficult. Everyone in c/newbiequestions repeats that dose escalation is important. I believe it, but I have never seen anyone show why, and…
1.8k
[Question] New Zealand — has anyone got a straight answer on dose escalation
Trying to settle this properly because the thread from last year went in circles. The claim: glucagon matters. The counter-claim: it is measurement error. Both sides…
1.8k
[Trial Data] TRIUMPH timeline — what we actually know vs what gets repeated
Trying to settle this properly because the thread from last year went in circles. The claim: glucagon matters. The counter-claim: it is measurement error. Both sides…